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In the nearly 60 years since Watson and Crick proposed the double helical structure of DNA, the molecule of heredity, waves of discoveries have made genetics the most thrilling field in the sciences. The study of genes and genomics today explores all aspects of the life with relevance in the lab, in the doctor’s office, in the courtroom and even in social relationships. In this helpful guidebook, one of the most respected and accomplished human geneticists of our time communicates the importance of genes and genomics studies in all aspects of life. With the use of core concepts and the integration of extensive references, this book provides students and professionals alike with the most in...
One can have a successful professional career, and a meaningful, personal life while struggling all the while with a common mental illness: bipolar disorder. This memoir describes the author's widely recognized research in the field of inherited metabolic disorders in children, his pivotal role as Dean of the Yale University School of Medicine and as Chief Scientific Officer of the Bristol-Myers Squibb Company, his contributions to public affairs, and his efforts as a teacher of medical, graduate, undergraduate, and high school students. These stories are interwoven with that of his personal encounter with bipolar disorder--one that has gone on for 60 years, and once nearly ended his life in a Prozac-precipitated suicide attempt. This is a narrative of hope and resilience, not one of desolation and despair.
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Genetic Factors in Nutrition presents the proceedings of the International Workshop on Genetic Factors in Nutrition, held in Teotihuacan, Mexico, on August 4-8, 1982. The papers explore the link between genetics and nutrition in the context of biological evolution. They provide examples of successful interaction between the two disciplines and consider some aspects of nutrient requirements, as well as utilization and consideration of methodological approaches to evaluate nutritional status, with an emphasis on malnutrition. Divided into six parts encompassing 29 chapters, this volume begins with an overview of genetics and nutrition from an evolutionary perspective, citing findings among Ame...
In the words of Disraeli, "To be conscious that you are ignorant of the facts is a great step to knowledge. " For most of us, the conscious awareness of relative ignorance is an uncomfortable aspect of daily life. New data appear in such inexorable profusion that the necessity for continuous retooling has joined death and taxes as an inescapable component of our destinies. Perhaps it is this "consciousness of ignorance" that accounts for the success of the preceding volumes of this new series. The Year in Metabolism and The Year in Endocrinology series were introduced with the avowed intention of "providing an efficient and enjoyable bridge between those who are creating new knowledge at the...