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In this first book to cover model systems, molecular mechanisms and clinical trials all in one volume internationally renowned scientists and clinicians provide a comprehensive treatment of neuroprotective strategies for all important neurological disorders. Following an overview of neurodegenerative, traumatic, and ischemic disorders, the book goes on to cover in vitro and animal model systems as well as cellular and molecular mechanisms. An extremely helpful analysis of clinical studies explains reasons for their success and failure, and the whole is rounded off with a look at the current challenges and hopes for the development of effective treatment strategies in the future.
Lewis Bokurtz is not saving the world. This isn’t that kind of story. His parents don’t keep him in a cupboard under the stairs. His teacher doesn’t lock him in a closet filled with broken glass. His friends have never treated him with disdain due to his expression of any unique supernatural powers. He desperately wishes they would. A thoughtful young boy yearns for adventure, like so many he has lived between the covers of his favorite books. When the discovery of a rusted iron coin hidden in the depths of a pond leads him to the towering black gates of the Iron Circus, he finds everything he ever wanted waiting just for him beneath the monolithic reaches of its imposing iron Big Top. But everything at the Iron Circus is not as it seems: the performers are all busy preparing for their spectacular upcoming show, almost too keen for Lewis’s help. Meanwhile, the sinister Ringmaster lurks in the shadows, his hollow smile a mask for sabotage and subterfuge. Can Lewis triumph over every challenge, ensure the show goes on, and live the adventure he’s always dreamed of? Or is this just not that kind of story?
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Brood is the true life account of an ordinary family who left the beautiful foothills and valleys of Mt. Judea, Arkansas, (commonly referred to as "Judy" for anyone who has a link to its past) and headed south into unfamiliar territories. This new world, also known as the great state of Texas, offered more suitable farming lands and the promise of a better future. With all earthly possessions stowed in covered wagons, the adventure began. Hope and happiness quickly turned to worry and fear as World War II dropped its uncertainties on the thresholds of homes already struggling to survive. The Heffley family was not immune to the sufferings of war. They did, however, summon the strength and de...
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This profile of Grammy award winning conductor Sir Georg Solti celebrates the musician's life and career, telling his story from his years as an assistant to conductor Toscanini during the Salzburg Festival to his legendary stint with the Vienna Philharmonic. ~ Cammila Collar, Rovi