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Single-Molecule Cellular Biophysics
Recent advances in single molecule science have presented a new branch of science: single molecule cellular biophysics, combining classical cell biology with cutting-edge single molecule biophysics. This textbook explains the essential elements of this new discipline, from the state-of-the-art single molecule techniques to real-world applications in unravelling the inner workings of the cell. Every effort has been made to ensure the text can be easily understood by students from both the physical and life sciences. Mathematical derivations are kept to a minimum whilst unnecessary biological terminology is avoided and text boxes provide readers from either background with additional information. 100 end-of-chapter exercises are divided into those aimed at physical sciences students, those aimed at life science students and those that can be tackled by students from both disciplines. The use of case studies and real research examples make this textbook indispensable for undergraduate students entering this exciting field.
Male-mediated Developmental Toxicity
Germ cells have a unique and critical role as the conduit for hereditary information. The issue of male germline mutagenesis and the effects on developmental defects in the next generation has become increasingly high profile in recent years. Understanding the mechanisms by which the germline is induced and maintained is one of the effective ways to treat infertility and cancer. Male-mediated Developmental Toxicity discusses these issues and provides analysis of the fundamental mechanisms of mutations covering both clinical and experimental aspects. It helps clarify the data explaining how genotoxicity involves multiple modes of action and highlights novel models and assays being used to assess germ cell genotoxicity. With a clear focus on the various mechanisms that could impact human health, this book is for postgraduate students and researchers in reproductive and developmental toxicology as well as those with an interest in the fields of genetically inherited diseases, developmental biology and, potentially, those with a more clinical background.
21st Century Prometheus
This book describes the evolving CBRN risk landscape and highlights advances in the “core” CBRN technologies, including when combined with (improvised) explosive devices (CBRNe threats). It analyses how associated technologies create new safety and security risks, challenging certain assumptions that underlie current control regimes. The book also shows how technologies can be enablers for more effective strategies to mitigate these risks. 21st-century safety and security risks emanating from chemical, biological, radiological and nuclear materials – whether resulting from natural events, accidents or malevolent use - are increasingly shaped by technologies that enable their developmen...
Visual Heritage: Digital Approaches in Heritage Science
How we understand our shared and individual heritage, interpret and disseminate that knowledge is increasingly central to contemporary society. The emerging context for such development is the field of heritage science. Inherently interdisciplinary, and involving both the Arts and Humanities, engineering, conservation and the digital sciences, the development of heritage science is a driver for change; socially, economically and technically. This book has gathered contributions from leading researchers from across the world and provides a series of themed contributions demonstrating the theoretical, ethical, methodological and technical methods which lie at the heart of heritage science. Arc...
Painting a Brand-New Picture of the New Era: RDI Annual Report 2021
中国社会科学院蓝迪国际智库项目于2015年4月正式启动，以问题导向、需求导向和项目导向为原则，旨在推动“一带一路”倡议的研究与实践，在智库研究、国际合作以及促进“一带一路”建设等方面开展了大量工作。本书是《2021，新时代的崭新画卷：蓝迪国际智库2021年度报告》的英文版，由蓝迪国际智库2021年重要活动、 合作机构、专家与团队、2022年展望四部分组成，全面记录在2021这个极其不平凡之年的所作所为充分，展示了中国新型智库的使命担当和中国社科院新型智库建设的显著成果。
The Coronavirus Pandemic and the Future: Virology, Epidemiology, Translational Toxicology and Therapeutics, Volume 2
This second volume chronicles the later stages of the outbreak of SARS-Cov-2 (COVID-19) and delineates the role of several disciplines in therapeutic and control measures highliting the response from specific coutries of note and efforts to repurpose and produce new therapeutics and vaccines. By addressing considerations of efficacy and safety of drugs and chemicals used to combat COVID-19, virtually in real-time, this book documents and highlights the advances in science and place the toxicology, pharmaceutical science, public health and medical community in a better position to advise in future epidemics.
The History of Customs in Sui, Tang and Five Dynasties
The book is the volume of “The History of Customs in Sui, Tang and Five Dynasties” among a series of books of “Deep into China Histories”. The earliest known written records of the history of China date from as early as 1250 BC, from the Shang dynasty (c. 1600–1046 BC) and the Bamboo Annals (296 BC) describe a Xia dynasty (c. 2070–1600 BC) before the Shang, but no writing is known from the period The Shang ruled in the Yellow River valley, which is commonly held to be the cradle of Chinese civilization. However, Neolithic civilizations originated at various cultural centers along both the Yellow River and Yangtze River. These Yellow River and Yangtze civilizations arose millennia...
The Coronavirus Pandemic and the Future: Virology, Epidemiology, Translational Toxicology and Therapeutics, Volume 1
By addressing considerations of efficacy and safety of drugs and chemicals used to combat COVID-19, virtually in real-time, this book documents and highlights the advances in science and place the toxicology, pharmaceutical science, public health and medical community in a better position to advise in future epidemics.
The Ethics of Neuroscience and National Security
New advances in neuroscience promise innovations in national security, especially in the areas of law enforcement, intelligence collection, and armed conflict. But ethical questions emerge about how we can, and should, use these innovations. This book draws on the open literature to map the development of neuroscience, particularly through funding by the Defense Advanced Research Projects Agency, in certain areas like behavior prediction, behavior modification, and neuroenhancement, and its use in the creation of novel weapons. It shows how advances in neuroscience and new technologies raise ethical issues that challenge the norms of law enforcement, intelligence collection, and armed confli...
