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The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS
Multidrug-resistant tuberculosis (TB) is caused by bacteria resistant to isoniazid and rifampicin, the two most effective first-line anti-TB drugs, originally developed and introduced in the 1950 and 1960s. Since 2008, the Forum on Drug Discovery, Development, and Translation of the Institute of Medicine has hosted or co-hosted six domestic and international workshops addressing the global crisis of drug-resistant TB, with special attention to the BRICS countries - Brazil, Russia, India, China, and South Africa. The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS is the summary of a workshop convened to address the current status of drug-resistant TB global...
Molecular Level Atomistic and Structural Insights on Biological Macromolecules, Inhibition, and Dynamics Studies
Everything in a living organism relies on biological macromolecules, which have the role of enzymatic chemical transformations, formation of structures, transportation, catalysis, and regulation of biological processes. They are complex biological structures that require an atomistic understanding. A molecular understanding of biological macromolecules has had a massive impact on the pharmaceutical, biotechnological, and chemical industries. Specifically, new enzymatic structures are being discovered through various experimental and computational methods, by describing an atomistic-level insight into function, mechanism, role in reactions and their inhibition. Those atom-level illustrations are mainly focused through enzyme kinetics, enzyme inhibition, mutational and conformational analysis through quantum mechanical and molecular dynamics methods.
Biotechnology
This book provides new information relating recent advances made in the field of plant secondary products. Besides the updation of chapters this edition also includes chapters on secondary metabolites of microorganisms (fungi and lichen).
China Satellite Navigation Conference (CSNC) 2012 Proceedings
Proceedings of the 3rd China Satellite Navigation Conference (CSNC2012) presents selected research papers from CSNC2012, held on 15-19 May in Guanzhou, China. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou system especially. They are divided into 9 topics to match the corresponding sessions in CSNC2012, which broadly covered key topics in GNSS. Readers can learn about the BeiDou system and keep abreast of the latest advances in GNSS techniques and applications. SUN Jiadong is the Chief Designer of the Compass/BeiDou system, and the Academician of Chinese Academy of Sciences; LIU Jingnan is a professor at Wuhan University, and the Academician of Chinese Academy of Engineering; YANG Yuanxi is a professor at China National Administration of GNSS and Applications, and the Academician of Chinese Academy of Sciences; FAN Shiwei is a researcher on satellite navigation.
ICAF 2019 – Structural Integrity in the Age of Additive Manufacturing
This book gathers papers presented at the 36th conference and 30th Symposium of the International Committee on Aeronautical Fatigue and Structural integrity. Focusing on the main theme of “Structural Integrity in the Age of Additive Manufacturing”, the chapters cover different aspects concerning research, developments and challenges in this field, offering a timely reference guide to designers, regulators, manufacturer, and both researchers and professionals of the broad aerospace community.
China Satellite Navigation Conference (CSNC) 2018 Proceedings
These proceedings present selected research papers from CSNC 2018, held during 23rd-25th May in Harbin, China. The theme of CSNC 2018 is Location, Time of Augmentation. These papers discuss the technologies and applications of the Global Navigation Satellite System (GNSS), and the latest progress made in the China BeiDou System (BDS) especially. They are divided into 12 topics to match the corresponding sessions in CSNC 2018, which broadly covered key topics in GNSS. Readers can learn about the BDS and keep abreast of the latest advances in GNSS techniques and applications.
Circulating Tumor Cells
It is well recognized that blood could be the optimal site for evaluating cancer, allowing easy and repeated access for determining prognosis, establishing molecular targets, evaluating the efficacy of therapy, detecting the earliest signs of recurrence, and even detecting cancer at its earliest and most curable stages. The analysis of cancer through blood samples is now known as the liquid biopsy and has been a rich source of research and clinical application. There has been an explosion of interest and progress in liquid biopsy technologies since the first edition of this book. The second edition will expand its focus to now include not only circulating tumor cells (CTC), but also other em...
Human Centered Computing
This book constitutes thoroughly reviewed, revised and selected papers from the 7th International Conference on Human Centered Computing, HCC 2021, held in virtually, due to COVID- 19, in December 2021. The 18 full and 9 short papers presented in this volume were carefully reviewed and selected from a total of 68 submissions. The conference focuses on the following three main themes as follows: Data such as Data Visualization, Big Data, Data Security, Hyper connectivity such as Internet of Things, Cloud Computing, Mobile Network and Collaboration such as Collective Intelligence, Peer Production, Context Awareness and much more.
Functional Genomics and Evolution of Photosynthetic Systems
New possibilities have been brought about by the stunning number of genomic sequences becoming available for photosynthetic organisms. This new world of whole genome sequence data spans the phyla from photosynthetic microbes to algae to higher plants. These whole genome projects are intrinsically interesting, but also inform the variety of other molecular sequence databases including the recent 'meta-genomic' sequencing efforts that analyze entire communities of organisms. As impressive as they are, are obviously only the beginning of the effort to decipher the biological meaning encoded within them. This book aims to highlight progress in this direction. This book aims toward a genome-level...
