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Signal Transduction
A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor – ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is d...
Signal Transduction
Signal Transduction is a well-illustrated, coherent look at cellular signaling processes. Beginning with the basics, it explains how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and then shows how these inputs are integrated and coordinated. The extensive color artwork provides the reader with a clearer comprehension of key topics, and margin notes are incorporated to highlight milestones in the evolution of signal transduction. This book serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields.
Signal Transduction
Signal Transduction, 2e, is a thorough, well-illustrated study in cellular signaling processes. Beginning with the basics, this book shows how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and further instructs how these inputs are integrated. Instruction continues with up-to-date, inclusive coverage of intracellular calcium, nuclear receptors, tyrosine protein kinases and adaptive immunity, and targeting transduction pathways for research and medical intervention. Signal Transduction, 2e, serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields. Up-to-date, inclusive coverage of targeting transduction pathways for research and medical intervention In-depth coverage of nuclear receptors, including steps in isolation of steroid hormones and the discovery of intracellular hormone receptors; tyrosine protein kinases and adaptive immunity; and intracellular calcium Extensive conceptual color artwork to assist with comprehension of key topics Instrumental margin notes highlight milestones in signaling mechanisms
The Book of Affinitive Life
The Book of Affinitive Life: Part 1 in Conjunction: The Book of Life is mainly about life on Earth concerning the invited signals of love that create addictions and eventually transcend into affinitive life. It is commonly characterized in the world as a passion, hobby, or bond to someone or something; and it is practiced or lived by means of a habitual lifestyle or habit by virtue of signal responsiveness in response to behavior in interaction with whom or what affinitive life centers on. The surprisingly interesting spiritual fact about the love signal is that it lies beyond ordinary experiences and supernaturally transcends into an acquired spirit that is grafted into your natural spirit ...
Signal Transduction
Signal Transduction is a text reference on cellular signalling processes. Starting with the basics, it explains how cells respond to external cues (hormones, cytokines, neurotransmitters, adhesion molecules, extracellular matrix etc), and shows how these inputs are integrated and co-ordinated. The first half of the book provides the conceptual framework, explaining the formation and action of second messengers, particularly cyclic nucleotides and calcium, and the mediation of signal pathways by GTP-binding proteins. The remaining chapters deal with the formation of complex signalling cascades employed by cytokines and adhesion molecules, starting at the membrane and ending in the nucleus, there to regulate gene transcription. In this context, growth is an important potential outcome and this has relevance to the cellular transformations that underlie cancer. The book ends with a description at the molecular level of how signalling proteins interact with their environment and with each other through their structural domains. Each main topic is introduced with a historical essay, detailing the sources, key observations and experiments that set the scene for recent and current work.
Life Sciences in Transition
These essays grew out of an effort at the EMBL to promote a new form of science communication on the social, ethical, and political issues that surround rapid change in the life sciences. Published in the Journal of Molecular Biology, these eighteen essays address the main topics of the future of the biosciences, biosciences and basic values, genomics and the globalization of biology, science miscommunication, and reproductive technologies. Hot topics such as cloning, genomics, reproductive technologies, heatlh care costs are addressed. Key Features * Significant to those in the life sciences and social sciences * Features an Introduction by Halldór Stefánsson * Published in conjunction with the prestigious European Molecular Biology Laboratory (EMBL)
Signal Transduction
A reference on cellular signaling processes, the third edition of Signal Transduction continues in the tradition of previous editions, in providing a historical overview of how the concept of stimulus-response coupling arose in the early twentieth century and shaped our current understanding of the action of hormones, cytokines, neurotransmitters, growth factors and adhesion molecules. In a new chapter, an introduction to signal transduction, the book provides a concise overview of receptor mechanisms, from receptor - ligand interactions to post-translational modifications operational in the process of bringing about cellular changes. The phosphorylation process, from bacteria to men, is discussed in detail. Signal transduction third edition further elaborates on diverse signaling cascades within particular contexts such as muscle contraction, innate and adaptive immunity, glucose metabolism, regulation of appetite, oncogenic transformation and cell fate decision during development or in stem cell niches. The subjects have been enriched with descriptions of the relevant anatomical, histological, physiological or pathological condition.
