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Personalized Health and Precision Medicine in Practice
So-called personalized health and precision medicine consist of a plethora of distinct endeavors. Ranging from pharmacogenomics to big data medicine, these endeavors are set out to tailor treatment and prevention to different combinations of data on the biological, behavioral, social, and environmental determinants of health. Currently reaching the trial of implementation across a diverse range of local and national contexts, these innovations call for a thorough empirical scrutiny of the normative, practical, and technical reconfigurations that they engender. Personalized/precision approaches to medicine demand substantive, normative work that consists in reforming social contracts in healthcare, and in ensuring a consistent commitment to change from both institutional actors and citizens.
Epigenetics and Responsibility
EPUB and EPDF available Open Access under CC-BY-NC-ND licence. We tend to hold people responsible for their choices, but not for what they can’t control: their nature, genes or biological makeup. This thought-provoking collection redefines the boundaries of moral responsibility. It shows how epigenetics reveals connections between our genetic make-up and our environment. The essays challenge established notions of human nature and the nature/nurture divide and suggest a shift in focus from individual to collective responsibility. Uncovering the links between our genetic makeup, environment and experiences, this is an important contribution to ongoing debates on ethics, genetics and responsibility.
Serendipity Science
This volume brings together for the first time the diverse threads within the growing field of serendipity research, to reflect both on the origins of this emerging field within different disciplines as well as its increasing influence as its own field with foundational texts and emerging practices. The phenomenon of serendipity has been described in many ways since Horace Walpole initially coined the term in 1754 to categorize those discoveries that happen by “both accidents and sagacity”. This book offers a sampling of perspectives from experts in serendipity research from organizational studies, management theory, information science and library studies, psychology, literature, comput...
Ethical Counselling and Medical Decision-Making in the Era of Personalised Medicine
This book offers an overview of the main questions arising when biomedical decision-making intersects ethical decision-making. It reports on two ethical decision-making methodologies, one addressing the patients, the other physicians. It shows how patients’ autonomous choices can be empowered by increasing awareness of ethical deliberation, and at the same time it supports healthcare professionals in developing an ethical sensitivity, which they can apply in their daily practice. The book highlights the importance and relevance of practicing bioethics in the age of personalized medicine. It presents concrete cases studies dealing with cancer and genetic diseases, where difficult decisions ...
Personalized Medicine
"Personalized Medicine investigates the recent movement for patients' involvement in how they are treated, diagnosed, and medicated; a movement that accompanies the increasingly popular idea that people should be proactive, well-informed participants in their own healthcare. While it is often the case that participatory practices in medicine are celebrated as instances of patient empowerment or, alternatively, are dismissed as cases of patient exploitation, Barbara Prainsack challenges these views to illustrate how personalized medicine can give rise to a technology-focused individualism, yet also present new opportunities to strengthen solidarity. Facing the future, this book reveals how medicine informed by digital, quantified, and computable information is already changing the personalization movement, providing a contemporary twist on how medical symptoms or ailments are shared and discussed in society"--Provided by publisher.
Integrative Approaches in Environmental Health and Exposome Research
Research on the relationship between health and the environment in a postgenomic context is increasingly aimed at understanding the various exposures as a whole, simultaneously taking into account data pertaining to the biology of organisms and the physical and social environment. Exposome research is a paradigmatic case of this new trend in environmental health studies. This book takes a multidisciplinary approach focusing on the conceptual, epistemological, and sociological reflections in the latest research on environmental and social determinants of health and disease. It offers a combination of theoretical and practical approaches and the authors are scholars from a multidisciplinary background (epidemiology, geography, philosophy of medicine and biology, sociology). Crucially, the book balances the benefit and cost of the integration of biological and social factors when modelling aetiology of disease.
Genetics and the Literary Imagination
This is the first book to explore the dramatic impact of genetics on literary fiction over the past four decades. After James Watson and Francis Crick's discovery of the structure of DNA in 1953 and the subsequent cracking of the genetic code, a gene-centric discourse developed which had a major impact not only on biological science but on wider culture. As figures like E.O. Wilson and Richard Dawkins popularised the neo-Darwinian view that behaviour was driven by genetic self-interest, novelists were both compelled and unnerved by such a vision of the origins and ends of life. This book maps the ways in which Doris Lessing, A.S. Byatt, Ian McEwan, and Kazuo Ishiguro wrestled with the reduct...
Metric Culture
Data and metrics play an unmistakably powerful role in today’s society. Over the years, their use has expanded to cover almost every sphere of everyday life. This book provides a critical investigation into what we can call a “metric culture” in which practices of self-tracking and quantification have become more popular than ever before.
The Handbook of DOHaD and Society
An indispensable guide for scholars completing interdisciplinary research in the field of the Developmental Origins of Health and Disease.
Afflicted
How medical education and practice can move beyond a narrow focus on biological intervention to recognize the lived experiences of illness, suffering, and death. In Afflicted, Nicole Piemonte examines the preoccupation in medicine with cure over care, arguing that the traditional focus on biological intervention keeps medicine from addressing the complex realities of patient suffering. Although many have pointed to the lack of compassion and empathy in medical practice, few have considered the deeper philosophical, psychological, and ontological reasons for it. Piemonte fills that gap, examining why it is that clinicians and medical trainees largely evade issues of vulnerability and mortalit...
