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Autoimmuno-Anti-Tumour Immunity (AATI) – Understanding the Immune Responses against “Self” & “Altered-self”
The brief description of tumours being “wounds that do not heal” by Dr Harold F. Dworak nearly three decades ago (N Engl J Med 1986) has provided not only a vivid illustration of neoplastic diseases in general but also, in retrospect conceptually, a plausible immunological definition of cancers. Based on our current understanding in the field, it could have even a multi-dimensional meaning attached with. This relates to several important issues which need to be addressed further, i.e. in terms of a close link between chronic inflammation and tumourigenesis widely observed; clinical and experimental evidence of immunity against tumours versus the highly immunosuppressive tumour microenvir...
NETosis 2: The Excitement Continues
NETosis, a form of cell death that manifests by the release of decondensed chromatin to the extracellular space, provides valuable insights into mechanisms and consequences of cellular demise. Because extracellular chromatin can immobilize microbes, the extended nucleohistone network was called a neutrophil extracellular trap (NET), and the process of chromatin release was proposed to serve an innate immune defense function. Extracellular chromatin NETs were initially observed in studies of neutrophils and are most prominent in these types of granulocytes. Subsequent studies showed that other granulocytes and, in a limited way, other cells of the innate immune response may also release nucle...
The Role of Pentraxins: From Inflammation, Tissue Repair and Immunity to Biomarkers
We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.
Neither Peace Nor Freedom
Patrick Iber tells the story of left-wing Latin American artists, writers, and scholars who worked as diplomats, advised rulers, opposed dictators, and even led nations during the Cold War. Ultimately, they could not break free from the era’s rigid binaries, and found little room to promote their social democratic ideals without compromising them.
Oxidants and Redox Signaling in Inflammation
During the last two decades, our view of the role of reactive oxygen species (ROS) in inflammatory processes has changed dramatically. ROS that are constantly produced at lower levels by living cells metabolizing oxygen contribute to normal cellular function and tissue homeostasis. ROS are produced at higher levels in inflammation and regulate the inflammatory response in specific ways. The role of ROS in inflammation is complex and primarily determined by their relative amount, chemical properties, reactivity, subcellular localization and molecular environment, specificity for their biological targets, and availability and mechanisms of antioxidant defense systems. This eBook comprises twel...
Skin Autoimmunity
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The Routledge Companion to Diasporic Jazz Studies
The Routledge Companion to Diasporic Jazz Studies recognizes the proliferation of jazz as global music in the 21st century. It illustrates the multi-vocality of contemporary jazz studies, combining local narratives, global histories, and cultural criticism. It rests on the argument that diasporic jazz is not a passive, second-hand reflection of music originating in the US, but possesses its own integrity, vitality, and distinctive range of identities. This companion reveals the contradictions of cultural globalization from which diasporic jazz cultures emerge, through 45 chapters within seven thematic parts: • What is Diasporic Jazz? • Histories and Counter-Narratives • Making, Dissemi...
Pattern Recognition and Image Analysis
The refereed proceedings of the First Iberial Conference on Pattern Recognition and Image Analysis, IbPria 2003, held in Puerto de Andratx, Mallorca, Spain in June 2003. The 130 revised papers presented were carefully reviewed and selected from 185 full papers submitted. All current aspects of ongoing research in computer vision, image processing, pattern recognition, and speech recognition are addressed.
Phagocytosis: Molecular Mechanisms and Physiological Implications
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
