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The partition of fluid between the vascular and interstitial compartments is regulated by forces (hydrostatic and oncotic) operating across the microvascular walls and the surface areas of permeable structures comprising the endothelial barrier to fluid and solute exchange, as well as within the extracellular matrix and lymphatics. In addition to its role in the regulation of vascular volume, transcapillary fluid filtration also allows for continuous turnover of water bathing tissue cells, providing the medium for diffusional flux of oxygen and nutrients required for cellular metabolism and removal of metabolic byproducts. Transendothelial volume flow has also been shown to influence vascula...
Lymphatic Structure and Function in Health and Disease serves as a resource book on what has been learned about lymphatic structure, function and anatomy within different organ systems. This is the first book to bring together lymphatic medicine as a whole, with in-depth analysis of specific aspects of lymphatics in different vascular pathologies. This book is a useful tool for scientists, practicing clinicians and residents, in particular, those in vascular biology, neurology, cardiology and general medicine. Chapters discuss topics such as ontogeny and phylogeny of lymphatics, lymphatic pumping, CNS lymphatics, lymphatics in transplant and lymphatic reconstruction. - Brings together lymphatic medicine as a whole, with an in-depth analysis of the specific basic science aspects of lymphatic structure and function - Covers the clinical aspects of lymphatics in different vascular pathologies - Co-published with the International Society of Neurovascular Diseases - Discusses lymphatic structure and function in all of the major organ systems
This book will be a comprehensive study of the lymphatic system and its immunological role. It will begin with lymphatic capillaries, their origin and development. It will treat lymph circulation, in general, with a special emphasis on lymph circulation in parenchymal organs. The next section will address lymph nodes, subcortical circulation and the conduit system. It will discuss organs with no lymphatic system, such as the brain. Finally, it will cover lymph composition and cells in the lymph. While primarily basic research, the volume will touch upon elements of the clinical, as well, broadening its scope and appeal.
Lymphatics and Lymph Circulation: Physiology and Pathology is a comprehensive account of the physiology and pathology of lymphatics and lymph circulation, with emphasis on the question of lymph flow as well as the problems of capillary filtration and diffusion in the connective tissue. These intricate processes are explained from a uniform point of view. Comprised of 27 chapters, this book begins with a discussion on the origin and architecture of the lymphatic system, paying particular attention to the discovery of lymphatics and lymph circulation; the phylogenesis and ontogenesis of lymphatics; and general and special anatomy of the lymphatic system. The second part explores the general physiology and pathology of the lymphatic system and includes chapters dealing with the role of the connective tissue in lymph formation; absorption into lymph capillaries; filtration and absorption through serous membranes; and lymph flow and composition. The remaining chapters consider the central nervous system and other organs such as the heart, lung, liver, kidney, and pancreas. This monograph will be useful for students, practitioners, and researchers in physiology and pathology.
This book provides a comprehensive account of vascular biology and pathology and its significance for health and disease. It systematically and chronologically explains how we came to our current understanding of the vasculature and it ́s function today, and describes in an entertaining way the diverse flaws and turns in science and medicine from the past. It thereby offers a complete and well-studied history on vascular biology and medicine. The book has an easy-to-read style and is written for students as well as scientists, physicians and lecturers in the field of biomedicine, human physiology, cardiology and hematology.
This atlas provides detailed information on the human lymphatic system in the head, neck and chest regions as well as the extremities, with more than 400 photographs and radiographs, including micro and macro views of the morphology. Much of the content is presented for the first time, such as the individual differences in lymphatic distribution, especially in the head neck region; characteristics of the indirect precollecting lymph vessel in the scalp; the lymphatic ampulla and diverticulum; and the transparent lymph node. Providing insights into the lymphatic anatomy, the book is an essential resource for medical and science students as well as therapists, clinicians and researchers working in this field.
Blood Vessels and Lymphatics on Organ Systems provides an introduction to the general and the specific characteristics of blood vessels and lymphatics in organ systems. It offers a structured, multidisciplinary approach to the broad field of vascular science, emphasizing both established and recent concepts. These include vascular networks such as those in the pineal, parathyroids, pancreas, adrenals, adipose tissue, and special senses; and functions of vascular endothelium. The book is organized into two parts. Part One on the general properties of blood vessels and lymphatics deals with the general aspects of the arteries, veins, microcirculation, and lymphatic channels. Part Two discusses the embryologic, morphologic, physiologic, pharmacologic, pathophysiologic, and pathologic characteristics of blood and lymph circulations in each of the important organ systems. This book was written for graduate students in the areas of blood and lymph circulation and for advanced research workers or clinicians seeking sources of information on advances in cardiovascular science.
The lymphatic system develops and functions in parallel with the blood circulatory system (termed the "hemovasculature") and accomplishes transport of interstitial fluids, dietary lipids, and reverse transport of cholesterol, immune cells, and antigens—providing a critical homeostatic fluid balance and transmission of immune cells and mediators back to the cardiovascular system. Although the daily flow of lymph (normally 1-2 L/day under unstressed conditions) is far lower than that of daily blood flow (which is 7,500 L/day), without the adequate functioning of the lymphatics, virtually all organs and tissues would acutely suffer many different physical and inflammatory stresses ranging fro...
The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.