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Leukaemia Research
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
Red Cell Shape
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Corpuscles
The shQpe of Qn erythrocyte is determined by Q delicQte equi librium of extrinsic Qnd intrinsic forces. It mQY chQnge during mQny PQtholog iCQI stQtes QS well QS du ri ng Q vQriety of ex perimentQI mQnipulQtions. Correct eVQluQtion of the fine detQi Is of the red cell shQpe thus provides i nformQtion of the g reQtest i mportQnce for the proper i nterpretQtion of the physi ology Qnd PQthophysiology of mQny Qnemic stQtes. In eXQmining red cells, the hemQtologist observes Q drop of blood spreQd on Q glQSS slide through the light microscope. This type of eXQminQtion is likely to remQin the routine tech nique of blood cytology for Q long time to come. Still, we should not forget thQt blood smeQrs...
Cellular Injury
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
International Review of Cytology
International Review of Cytology
Red Cell Rheology
Hemolysis during filtration through micropores studied by Chien et al. [I] showed a dependence on pressure gradient and pore diameter that, at the time of publication, did not permit an easy interpretation of the hemolytic mechanism. Acting on the assumption that thresholds of hemolysis are easier to correlate with physical forces than extents of hemolysis, we performed a series of experi ments repeating some of the conditions reported in [I] and then focusing on low L1P in order to define better the thresholds of hemolysis for several pore sizes. Employing a model of a deformed red cell shape at the pore entrance (based on micropipette observations) we related the force field in the fluid t...
The Leukemias: Etiology, Pathophysiology, and Treatment
The Leukemias: Etiology, Pathophysiology, and Treatment documents the proceedings of an International Symposium on The Leukemias: Etiology and Pathophysiology, held at Henry Ford Hospital, Detroit, Michigan, 8-10 March 1956. This volume gives the present complex position of leukemic etiology and pathophysiologic disturbance, a much needed knowledge of detailed leukocytic functions and comprehensive thought on the therapy of the leukemias. It also establishes a basis of comparison with the earlier works of Downey and Forkner in this field in the late thirties and thus makes it possible to see with some clarity the extent of progress made. The volume contains 39 papers organized into nine part...
Pade Approximants
The first edition of this book was reviewed in 1982 as "the most extensive treatment of Pade approximants actually available." This second edition has been thoroughly updated, with a substantial new chapter on multiseries approximants. Applications to statistical mechanics and critical phenomena are extensively covered, and there are newly extended sections devoted to circuit design, matrix Pade approximation, and computational methods. This succinct and straightforward treatment will appeal to scientists, engineers, and mathematicians alike.
Red Cell Shape
This monograph is a collection of invited contributions from a group of investiga tors who share a common interest in the interrelationships between the shape, struc ture, and functional characteristics of normal and pathologic erythrocytes. Most of the authors participated in a workshop on red cell shape held in June, 1972 at the Institute of Cell Pathology, Hopital de Bicetre, Paris. We hope that these various contributions on the physiology, pathology, and ultrastructure of red cell shape will be useful and stimulating for other investigators interested in the correlation of shape and structure with the biochemistry and biophysics of the red cell. The text is divided into four sections. S...
