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This volume constitutes the refereed proceedings of the 19th International Conference on Business Process Management, BPM 2021, held in Rome, Italy, in September 2021. The 23 full papers, one keynote paper, and 4 tutorial papers presented in this volume were carefully reviewed and selected from 92 submissions. The papers are organized in topical sections named: foundations, engineering, and management.
HIV-Associated Neurocognitive Disorders: Molecular and Cellular Mechanisms and Clinical Manifestations is a comprehensive volume on the field of HIV-Associated Neurocognitive Disorders (HAND) as well as its associated comorbidities. Covering clinical manifestations as well as molecular and cellular mechanisms, this book discusses available macaque and rodent animal models of HAND, epigenetic regulation, and signaling pathways underlying symptoms. Chapters also cover prevention and therapeutic strategies, as well as diagnosis and biomarkers associated with disease outcomes. This volume is appropriate for basic research and clinical investigators working in the area of HIV-1 infection. - Provides an in-depth exploration of the clinical manifestations of HAND and its comorbidities - Includes detailed assessments of the molecular and cellular mechanisms underlying HAND symptoms - Examines animal models for studying HAND, including macaque and rodent models - Presents insights into epigenetic regulation and signaling pathways implicated in HAND - Covers prevention, therapeutic strategies, and diagnostic approaches
An international symposium on `Ocean, River and Lakes: Energy and Substance Transfers at Interfaces' was held in Nantes, France in October 1996. It was the third International Joint Conference on Limnology and Oceanography which brings together specialists of both environments. Considered to be necessary in Europe, this confrontation of two different aspects of common subjects could produce innovative approaches. The main purpose concerns scientific researches relative to the interfaces between various aquatic environment compartments. The principal treated topics are bioavailability and mobility of substances, influence of biotic and abiotic factors on transfers, and fluxes at the interfaces. It is particularly interesting to note the contribution of Limnologists and Oceanographers on the impact of nutrients and pollutants, and flux quantification of river basin inputs. As well as scientists, this book is also of interest to all engineers and consultants involved in teaching and working in aquatic management, restoration and enhancement.
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Cutaneous lymphoid infiltrates which are suspicious for lymphoma, are always important challenges for the general pathologist who faces them occasionally. Many times they are also difficult even for the dermatopathologist, and the most modern diagnostic weapons sometimes play a crucial role in the differential diagnosis with other non-malignant entities, as well as between the different types of lymphomas. Clinically, they sometimes simulate many other conditions, and are not always easy to be recognise by the dermatologist. In 2005, a new classification of cutaneous lymphomas was published, in an attempt to achieve a better comprehension of the nature and behaviour of these tumours. Neverth...
This Book of Abstracts is the main publication of the 74th Annual Meeting of the European Federation of Animal Science (EAAP). It contains abstracts of the invited papers and contributed presentations of the sessions of EAAP's eleven Commissions: Animal Genetics, Animal Nutrition, Animal Management and Health, Animal Physiology, Cattle Production, Sheep and Goat Production, Pig Production, Horse Production and Livestock Farming Systems, Insects and Precision Livestock Farming.
Skin cancer is the most frequent malignancy in humans and its incidence is still increasing. This situation calls for major efforts to manage the disease. Preventive measures must include reduced UV exposure and an enhanced common awareness of skin lesions. Advanced surgical techniques allow safe removal with excellent cosmetic results. In many cases alternative treatment modalities such as radiotherapy, cryosurgery and photodynamic therapy are applicable. The development of optimal sun screens and UV-protective clothes, new tools for early diagnosis of malignant lesions including videomicroscopy, improved evaluation of biopsy material and new treatment schemes will contribute to better patient care. New developments in therapy including pegylated interferons, cytokine-inducing molecules, monoclonal antibodies and vaccination approaches using peptides, dendritic cells, viruses or nDNA give hope for well-tolerated and efficient treatments.