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First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.This volume focuses on activins and inhibins.
The systematic development of software systems is a central task of computing science. A software system is the result of putting together knowledge about the application, the requirements and the structures of computing science. Under the heading CIP (Computer-aided Intuition-guided Programming), a group of researchers led by Prof. F.L. Bauer and Prof. K. Samelson started work in 1975 in the direction of formal program specification, transformational programming, and tool supportfor program development. The collection of papers in this volume presents examples of a formal approach to programming language concepts and program development based on algebraic specifications and program transformations. Examples are also presented of evolutions and modificationsof the original ideas of the CIP project. The topics range from descriptionsof the program development process to derivations of algorithms from specifications. The volume is dedicated to Prof. F.L. Bauer.
This volume presents a short guide to the extensive literature concerning semir ings along with a complete bibliography. The literature has been created over many years, in variety of languages, by authors representing different schools of mathematics and working in various related fields. In many instances the terminology used is not universal, which further compounds the difficulty of locating pertinent sources even in this age of the Internet and electronic dis semination of research results. So far there has been no single reference that could guide the interested scholar or student to the relevant publications. This book is an attempt to fill this gap. My interest in the theory of semir...
Developmental cancer products (oncodevelopmental markers, ODM) not only serve as diagnostic and prognostic indicators but also may be used to study the nature of the carcinogenic process and the biology of tumors. For many years oncologists have searched for markers of cancer cells that would permit unequivocal recognition of cancer in contrast to noncancerous tissue. The earliest and still most widely used method of identification of cancer tissue or cells is the structural resemblance of cancer tissue to fetal or immature tissue. Pathologists not only recognize cancer by its morphologic similarity to fetal tissues, but also in many instances can relate the behavior of a given tumor to the ...
Completing the PIR series, this volume summarizes the major advances made in the local and systemic use of bone morphogenetic proteins (BMPs). Chapters are dedicated to the regulation of BMP-signaling pathways; biological actions of BMPs in bone, cartilage, and teeth; clinical applications; and the potential systemic use of BMPs for tissues beyond bone. The authors are all recognized experts in the field of tissue engineering and regeneration.
Completely revised and updated, the 2nd edition of The Handbook of Medicinal Chemistry draws together contributions from authoritative practitioners to provide a comprehensive overview of the field as well as insight into the latest trends and research. An ideal companion for students in medicinal chemistry, drug discovery and drug development, while also communicating core principles, the book places the discipline within the context of the burgeoning platform of new modalities now available to drug discovery. The book also highlights the role chemistry has to play in wider target validation and translational technologies. This is a carefully curated compilation of writing from global experts using their broad experience of medicinal chemistry, project leadership and drug discovery and development from an industry, academic and charity perspective to provide unparalleled insight into the field.
Carbon dots (CDs) as an emerging carbon nanomaterial have attracted considerable attention and have been widely used in numerous fields. When compared with semiconductor quantum dots and organic dyes, CDs have a low toxicity, good biocompatibility and good anti-photobleaching. These qualities give them the potential to be a greener optical probe than other types of quantum dots and organic dyes. Covering several common synthesis strategies, including biomass synthesis, large-scale synthesis and sustainable synthesis technology, this book focuses on the green synthesis of CDs and their applications in the fields of bioanalytical, catalytic, biomedical, and environmental sciences. It is a useful reference for anyone working in green chemistry, analytical chemistry, biomedical or environmental science.