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Huntington's disease (HD) is one of the most common dominantly inherited neurodegenerative disorders, characterized by a clinical trial of movement disorder, cognitive deficits, and psychiatric symptoms. Huntington's Disease: Pathogenic Mechanisms and Implications for Therapeutics, reviews the most up-do-date content on HD pathogenic mechanisms and cutting-edge testing of therapeutic strategies for HD. Chapters explore areas such as, normal huntingtin biology in brain development and function, genetic modifiers of HD in patients, molecular pathogenic mechanism in HD, and mechanisms underlying selective neuronal vulnerability - Reviews the clinical course and genetics of HD - Reviews the biol...
The no-punches pulled autobiography of former MP Frank Howard, who went from prison to federal politics in a career that saw him win ten elections over almost three decades.
Howard Pawley, former Premier of Manitoba (1981-88) led the province during one of the most turbulent periods in its history. Elected at the outset of a serious national recession, his government successfully implemented social democtatic policies that ran counter to the neo-conservative trends that dominated the period, including job creation, labour reform, and human rights legislation. But his greatest challenge was over French-language rights, an explosive two-year debate that left the province badly divided and embroiled in the complicated maneuvering between the national government and Quebec serparatists. The political and public fallout from the French-language issue echoed through M...
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Profiles the work of dynamic Sydney based architectural firm.
Presents information supplied by manufacturers and distributors about pharmaceuticals available for use in Canada. Organized by trade name. Includes a section on Canadian drug regulations.