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Design and Analysis of Vaccine Studies
As well as being a reference for the design, analysis, and interpretation of vaccine studies, the text covers all design and analysis stages, from vaccine development to post-licensure surveillance, presenting likelihood, frequentists, and Bayesian approaches.
Statistical Models in Epidemiology, the Environment, and Clinical Trials
This IMA Volume in Mathematics and its Applications STATISTICAL MODELS IN EPIDEMIOLOGY, THE ENVIRONMENT,AND CLINICAL TRIALS is a combined proceedings on "Design and Analysis of Clinical Trials" and "Statistics and Epidemiology: Environment and Health. " This volume is the third series based on the proceedings of a very successful 1997 IMA Summer Program on "Statistics in the Health Sciences. " I would like to thank the organizers: M. Elizabeth Halloran of Emory University (Biostatistics) and Donald A. Berry of Duke University (Insti tute of Statistics and Decision Sciences and Cancer Center Biostatistics) for their excellent work as organizers of the meeting and for editing the proceedings. ...
Statistics in Genetics
Though the Genome Project will eventually result in the sequencing of the human genome, as well as the genomes of several other organisms, there will still be a need for good statistics for family studies of complex diseases. The papers in this volume are contributions by some of the leading researchers in the field to the current topics in statistical genetics. One section deals with DNA sequence matching and issues related to forensics, while another deals with statistical problems of modeling phylogenies and inferential difficulties related to the complex tree structures produced, as well as the method of coalescence.
Charting the Next Pandemic
This book provides an introduction to the computational and complex systems modeling of the global spreading of infectious diseases. The latest developments in the area of contagion processes modeling are discussed, and readers are exposed to real world examples of data-model integration impacting the decision-making process. Recent advances in computational science and the increasing availability of real-world data are making it possible to develop realistic scenarios and real-time forecasts of the global spreading of emerging health threats. The first part of the book guides the reader through sophisticated complex systems modeling techniques with a non-technical and visual approach, expla...
Global Epidemics, Local Implications
Ultimately, this book shows how these responses underscore the importance of immigrant resources for developing public health interventions.
Atlas of Forecasts
Forecasting the future with advanced data models and visualizations. To envision and create the futures we want, society needs an appropriate understanding of the likely impact of alternative actions. Data models and visualizations offer a way to understand and intelligently manage complex, interlinked systems in science and technology, education, and policymaking. Atlas of Forecasts, from the creator of Atlas of Science and Atlas of Knowledge, shows how we can use data to predict, communicate, and ultimately attain desirable futures. Using advanced data visualizations to introduce different types of computational models, Atlas of Forecasts demonstrates how models can inform effective decision-making in education, science, technology, and policymaking. The models and maps presented aim to help anyone understand key processes and outcomes of complex systems dynamics, including which human skills are needed in an artificial intelligence-empowered economy; what progress in science and technology is likely to be made; and how policymakers can future-proof regions or nations. This Atlas offers a driver's seat-perspective for a test-drive of the future.
China’s Transition to a New Phase of Development
The Chinese economy is currently undergoing fundamental changes. In this context, the 2022 China Update examines the key characteristics of China’s transition towards a new phase of economic growth and development. This year’s update book covers a range of diverse topics that reflect the complex and changing nature of the economy. It explores critical questions: Why does China need a new development paradigm, and what is the best way to achieve it? What are China’s choices when faced with the restructuring of global industrial value chains? What key roles will domestic consumption play in the next phase of China’s development? What does the digital transformation mean for the Chinese economy? What has been the domestic impact of the Covid-19 pandemic on income inequality and labour market outcomes? What pathways exist for China in its transition towards carbon neutrality? How does China’s emissions-trading market compare with that of Europe? How will China’s carbon neutrality strategy affect the Australian economy? What are the political factors influencing bilateral trade flows between China and its trading partners? And what is at stake for China–US relations?
Anti/Vax
Antivaxxers are crazy. That is the perception we all gain from the media, the internet, celebrities, and beyond, writes Bernice Hausman in Anti/Vax, but we need to open our eyes and ears so that we can all have a better conversation about vaccine skepticism and its implications. Hausman argues that the heated debate about vaccinations and whether to get them or not is most often fueled by accusations and vilifications rather than careful attention to the real concerns of many Americans. She wants to set the record straight about vaccine skepticism and show how the issues and ideas that motivate it—like suspicion of pharmaceutical companies or the belief that some illness is necessary to go...
Quantitative Evaluation of HIV Prevention Programs
How successful are HIV prevention programs? Which HIV prevention programs are most cost effective? Which programs are worth expanding and which should be abandoned altogether? This book addresses the quantitative evaluation of HIV prevention programs, assessing for the first time several different quantitative methods of evaluation. The authors of the book include behavioral scientists, biologists, economists, epidemiologists, health service researchers, operations researchers, policy makers, and statisticians. They present a wide variety of perspectives on the subject, including an overview of HIV prevention programs in developing countries, economic analyses that address questions of cost effectiveness and resource allocation, case studies such as Israel’s ban on Ethiopian blood donors, and descriptions of new methodologies and problems.
Knowledge Guided Machine Learning
Given their tremendous success in commercial applications, machine learning (ML) models are increasingly being considered as alternatives to science-based models in many disciplines. Yet, these "black-box" ML models have found limited success due to their inability to work well in the presence of limited training data and generalize to unseen scenarios. As a result, there is a growing interest in the scientific community on creating a new generation of methods that integrate scientific knowledge in ML frameworks. This emerging field, called scientific knowledge-guided ML (KGML), seeks a distinct departure from existing "data-only" or "scientific knowledge-only" methods to use knowledge and d...
