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Basics in Primary Knee Arthroplasty
This book supplies all the information that the young orthopaedic surgeon needs to know when preparing to perform total or partial knee replacement for the first time and also provides more experienced surgeons with a comprehensive general update on the basics. After an opening section on anatomy and kinematics of the knee, patient management during the pre-, peri-, and postoperative phases is covered in detail with the aid of numerous illustrations. The final section considers postoperative patient evaluation, outcome measurements, and the value of registries. Readers will gain a sound understanding of the scientific basis underlying management decisions, of component design philosophies, and of the rationale for preferences such as mechanical alignment and ligament balancing. The pros and cons of a variety of management choices are explained, and guidance provided on patient selection. Surgical techniques are presented on high-quality videos and many tips and tricks are highlighted to help the inexperienced to cope with challenging situations.
Official Register
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House documents
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Innovations for Next-Generation Antibody-Drug Conjugates
Antibody-drug conjugates (ADCs) stand at the verge of a transformation. Scores of clinical programs have yielded only a few regulatory approvals, but a wave of technological innovation now empowers us to overcome past technical challenges. This volume focuses on the next generation of ADCs and the innovations that will enable them. The book inspires the future by integrating the field’s history with novel strategies and cutting-edge technologies. While the book primarily addresses ADCs for solid tumors, the last chapter explores the emerging interest in using ADCs to treat other diseases. The therapeutic rationale of ADCs is strong: to direct small molecules to the desired site of action (...
