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Charlie and the Tortoise
Charlie and the Tortoise shares the journey of how Charles Darwin discovered the connections between all animals on an adventure to some very unique islands.
Immunological Disorders in Mice
Immunological Disorders in Mice focuses on immunological reactions and diseases based on models provided through studies on genetically based immunological disorders in inbred strains of mice. The book discusses various defects affecting all levels of immunological response, featuring new data on "classical" mutations, as well as information regarding lesser known immune defects. New areas presented include genetic manipulation, ontogenetic aspects, clinical implications, the effect of drugs on immunodefective strains, and neuroendocrine regulation. A critical evaluation of the data presented through these studies on immune disorders in mice will facilitate the understanding of immunological processes and have significant application in clinical practice. Theoretical immunologists, animal breeding companies, and clinical immunologists will find this text invaluable.
The Pathology of Vessels
Vascular pathology is essentially based on a transverse, the main basic lesions, this book provides precise multi-organ approach to pathology. It has been the descriptions in all of the main areas : atherosclerotic, subject of only a few reference works as it tends to be inflammatory, dysplastic, and traumatic diseases, etc. ignored by organ specialists. However, the vascular Throughout this book, the lesions are precisely system is widely distributed in all tissues ; it is modelled described with identification of the various recognized very early during organogenesis by haemodynamic syndromes and discussion of the main established factors, it possesses a remarkable reactivity and pathophys...
Nontuberculous Mycobacterial Disease
This book is a comprehensive and authoritative source on nontuberculous mycobacterial (NTM) pathogens and diseases and their appropriate management, with a focus on lung disease. NTM diseases, especially lung diseases, are increasing in prevalence in the U.S. and internationally with concomitant growing interest in a broad section of the medical community. Often merely included in coverage of tuberculosis, many aspects of NTM organisms and diseases are actually very different than TB. These differences are not intuitive or trivial and frequently result in suboptimal management of NTM patients. This book addresses these gaps in the literature with chapters on microbiology, pathophysiology, epidemiology, the various diseases that can stem from NTM, and their particular management. There is also coverage on prevention and NTM as a public health problem. For pulmonologists and infectious disease physicians, this is the definitive resource on nontuberculous mycobacteria.
Immunopathology in Toxicology and Drug Development
This book provides a fundamental understanding of immunopathology and immunopathologic processes, with particular attention to nonclinical toxicology studies. Chapters provide organ system–based summaries of spontaneous pathology and common responses to xenobiotics. A companion volume, Immunopathology in Toxicology and Drug Development: Volume 1, Immunobiology, Investigative Techniques, and Special Studies, offers an overview of general immunobiology, cells of the immune system, signaling and effector molecules, and immunopathology assays. These informative and strategic books were created in response to the large segment of drug development that focuses on chronic diseases, many of which involve alterations to the immune system. Therapies that target these diseases commonly involve some form of immunomodulation. As a result, the two volumes of Immunopathology in Toxicology and Drug Development are critical texts for individuals involved in diverse aspects of drug development. Readers will acquire a thorough understanding of immunopathology for detection and accurate interpretation of pathologic effects of xenobiotics on the immune system.
Handbook of Clinical Neuroepidemiology
In recent years there have been significant advances in the knowledge of risk factors, gene-environment interactions, incidence, prevalence, outcomes, and prevention strategies of many neurological disorders. These advances have been accompanied by developments in study design methodologies and statistical analysis. This handbook bridges the gap between current neuroepidemiological knowledge and its evidence-based application in everyday practice.
Alzheimer's Disease and Related Disorders
A progress report on the cutting-edge research into Alzheimer‘s Disease and other forms of dementia, this important volume has particular emphasis on topics that are applicable to clinical practice.In this latest instalment, Serge Gauthier, Philip Scheltens and Jeffrey Cummings cover some of the emerging therapies for Alzheimer‘s Disease, including
Respiratory Treatment and Prevention
The goal of this book is to further insight into the challenges related to respiratory health. Medical experts present their lines of scientific investigations on how to contain the disease, care for patients, and use preventive measures, with a focus on pulmonary-related disorders. Progress in the diagnostics and treatment of major infectious diseases affecting humanity such as tuberculosis, malaria, fungal and viral contagions is tackled. Other chapters provide some background information on the mechanisms and prevention of non-communicable diseases. New aspects of the etiology of sarcoidosis, air pollution-related lung cancer, and sleep disordered breathing are presented. Preventive measures of health in general and respiratory health in particular cannot do without a reminder of cigarette smoke avoidance and the respiratory aftermath of the smoking habit. The book presents scientific evidence-based practice knowledge. It is intended for healthcare professionals, specifically pulmonary specialists, primary care physicians, and all scientifically-minded individuals involved in the care of patients.
Monoclonal Antibodies against Bacteria
Monoclonal Antibodies against Bacteria, Volume I explores the generation, characterization, and utilization of monoclonal antibodies against bacteria and on other monoclonal products relevant to antibacterial immune responses. Organized into 12 chapters, this book begins with a discussion on monoclonal antibodies against bacteria, encompassing its scope, research, and directions. It shows that the coordinated use of antisera and panels of monoclonal antibodies is proving useful for classification as a diagnostic tool with prognostic implications in the case of pathogens, or as a preliminary step in taxonomy. Also, monoclonal antibodies hold great potential as instruments in working with bact...
