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'An absolute page-turner' Mail on Sunday Dear Mr. M, I'd like to start by telling you that I'm doing better now. I do so because you probably have no idea that I was ever doing worse. Much worse, in fact, but I'll get to that later on. Mr. M is being watched. As a famous writer, he is no stranger to the limelight, although interest in his work has been dwindling of late. His print runs are smaller than they used to be, as are the crowds at his bookshop signings . . . Our narrator clearly takes a keen interest in M.'s work, and indeed in every aspect of his life. But what exactly are his intentions? And to what does Mr. M owe the honour of his undivided attention? Our narrator seems to be no ...
'A suspenseful mystery... Deeply moving and psychologically affecting' Alex Michaelides, author of The Silent Patient ONE SON LIED. ONE SON DIED. Alice's son is dead. Indigo's son is accused of murder. Indigo is determined to prove her beloved Kane is innocent. She is helped by a kind stranger who takes an interest in her situation. But little does she know that her new friend has her own agenda... Alice can't tell Indigo who she really is. She wants to understand why her son was killed. But how long will it take for Indigo to discover her identity? And what other secrets will come out as she digs PRAISE FOR KEEP HIM CLOSE: 'A tense drama' Sunday Times 'A beautiful and heart-breaking story that I can't stop thinking about. Simply stunning.' Jo Jakeman, author of Safe House 'Powerfully written and packs a real emotional punch.' Cara Hunter, author of Close to Home 'A magnetic, all consuming read. A heart-breaking suspense which deals with love in all its forms.' Gytha Lodge, author of She Lies in Wait
Handbook of Cell Signaling, Three-Volume Set, 2e, is a comprehensive work covering all aspects of intracellular signal processing, including extra/intracellular membrane receptors, signal transduction, gene expression/translation, and cellular/organotypic signal responses. The second edition is an up-to-date, expanded reference with each section edited by a recognized expert in the field. Tabular and well illustrated, the Handbook will serve as an in-depth reference for this complex and evolving field. Handbook of Cell Signaling, 2/e will appeal to a broad, cross-disciplinary audience interested in the structure, biochemistry, molecular biology and pathology of cellular effectors. - Contains over 350 chapters of comprehensive coverage on cell signaling - Includes discussion on topics from ligand/receptor interactions to organ/organism responses - Provides user-friendly, well-illustrated, reputable content by experts in the field
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The controversial ex-mayor of New York speaks out on his years in office, the people, and the policies of "the Big Apple".
NEW YORK TIMES BESTSELLER * NEW YORK TIMES NOTABLE BOOK OF 2019 * WINNER OF THE J ANTHONY LUKAS WORK-IN-PROGRESS AWARD * FINANCIAL TIMES’ BEST BOOKS OF 2019 * NPR FAVORITE BOOKS OF 2019 * FINALIST FOR THE FINACIAL TIMES/MCKINSEY BUSINESS BOOK OF 2019 * KIRKUS REVIEWS BEST BOOKS OF 2019 * SCHOOL LIBRARY JOURNAL BEST BOOKS OF 2019 “Superb…Among the best books ever written about an American corporation.” —Bryan Burrough, The New York Times Book Review Just as Steve Coll told the story of globalization through ExxonMobil and Andrew Ross Sorkin told the story of Wall Street excess through Too Big to Fail, Christopher Leonard’s Kochland uses the extraordinary account of how one of the ...
Since the introduction of balloon angioplasty for the relief of coronary artery stenoses and of anginal symptoms in patients with coronary artery disease by Andreas Griintzig in 1977, the field of interventional technology and treatment strategies has grown enormously. For the reduction of hemodynamically significant coronary artery stenoses balloon angioplasty is the standard and reference method with a high primary success and low complication rate. Because of the relatively high recurrence rates of 30-40% of balloon angioplasty a whole family of different angioplasty techniques has been developed since then. Among those are atherectomy devices, laser angioplasty, radiofrequency angioplast...
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Provides a comprehensive set of articles describing the use and application of state-of-the-art methodologies to identify and characterize these GTPases and their expanding list of regulators and effectors. This work also includes methodologies focused on biochemical, molecular and advanced imaging techniques.