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Bioinorganic Chemistry
An updated, practical guide to bioinorganic chemistry Bioinorganic Chemistry: A Short Course, Second Edition provides the fundamentals of inorganic chemistry and biochemistry relevant to understanding bioinorganic topics. Rather than striving to provide a broad overview of the whole, rapidly expanding field, this resource provides essential background material, followed by detailed information on selected topics. The goal is to give readers the background, tools, and skills to research and study bioinorganic topics of special interest to them. This extensively updated premier reference and text: Presents review chapters on the essentials of inorganic chemistry and biochemistry Includes up-to...
Understanding Autism
Taking an all-inclusive look at the subject, Understanding Autism: From Basic Neuroscience to Treatment reviews state-of-the-art research on the diagnosis, treatment, and prevention of autism. The book addresses potential mechanisms that may underlie the development of autism and the neural systems that are likely to be affected by these molecular,
Mitigation and Financing of Seismic Risks: Turkish and International Perspectives
Huge economic losses from natural disasters, including nearly 100 000 fatalities world wide in 1999 alone, gave rise to a renewed recognition by government, industry and the public that national governments and international agencies cannot simply go on as they have in the past. Changes in financial cover, better enforcement procedures for building standards, better business contingency planning, and well developed emergency response were demanded from all sides. In this volume an international group of experts present recent research on the variety of approaches adopted by different countries to assess natural hazard risks and the incentives for mitigating and financing them, the particular focus being in earthquake risks. The volume also presents an in-depth summary of recent reforms in Turkey related to seismic risks, with comparative research from many other countries. Linkages are emphasised between science and engineering infrastructure, insurance and risk management, and public policy.
Cytochrome P450
This authoritative Fourth Edition summarizes the advances of the past decade concerning the structure, mechanism, and biochemistry of cytochrome P450 enzymes, with sufficient coverage of earlier work to make each chapter a comprehensive review of the field. Thirteen chapters are divided into two detailed volumes, the first covering the fundamentals of cytochrome P450 biochemistry, as well as the microbial, plant, and insect systems, and the second exclusively focusing on mammalian systems. Volume 1 begins with an exploration of the biophysics and mechanistic enzymology of cytochrome P450 enzymes, with a discussion of the structures of P450 enzymes and their electron donor partners, the mecha...
Anticoagulation Therapy
The available parenteral and oral anticoagulants have a large clinical use. Understanding biochemistry of anticoagulants may help to improve therapeutic strategies. Resistance to vitamin K antagonist drugs might be a problem for rodent populations. Patients who have thrombogenic risk factors should be anticoagulated. The need for cardiac implantable electronic devices is increasing, and there is a substantial number of patients who are on oral anticoagulant therapy. Prothrombin complex concentrate and other plasma concentrates are useful to deal with over-coagulated situations. The efficacy and safety of non-vitamin K antagonist oral anticoagulants have been proven in large phase III trials. The real-world data suggest even better outcomes with these agents compared to vitamin K antagonists.
User-Centric Technologies and Applications
'Context' is defined as ‘any information that can be used to characterize the situation of an entity’. Nowadays, the increasing availability of communication networks, the miniaturization and progressive reduction in the cost of sensors and the penetration of advanced mobile personal devices make possible to collect and process data from multiple sources and combine them in order to automatically infer knowledge about the user’s situation. Thus, the CONTEXTS Workshop aims at gathering advances on key elements that enable the design and deployment of personalized ubiquitous context-aware services and natural non-intrusive methods for interaction. The Workshop is organized and funded by the CONTEXTS Programme, one of the largest cooperative research initiatives in Madrid, with the participation of institutions from all over Spain and with the support of international experts. The CONTEXTS Programme focuses on advancing the key elements in frontier communications and location technologies, data processing and multisensor fusion and paradigms for intelligent/adaptative management, which make feasible the development of advanced personalized applications for ambient intelligence.
Dioxygen-dependent Heme Enzymes
This book highlights the many and varied catalytic activities of O2-dependent heme-iron enzymes, including monoxygenases and cytochrome P450, dioxygenases, oxidases and model heme systems required for postgraduate students and researchers in biochemistry and metallobiology.
