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This authoritative reference presents the modern concepts of mesenchymal stem cells (MSCs) and biomaterials as they pertain to the dental field. The book is organized around three main topics: MSCs biology, advanced biomaterials, and clinical applications. The chapters present basic information on stem cell biology and physiology, modern biomaterials that improve bone tissue regeneration, the biomatrices like platelet-rich fibrin (PRF) used to functionalize the biomaterials surface, the strategic and safe intraoral seats of harvesting, the new sources for MSCs, as well as the future perspectives and new challenges in these exciting fields. The contributors are top scientists with a great deal of experience in regenerative dentistry and biomedical research. They offer an international perspective and are richly cross-disciplinary, representing academia, research, and industry. MSCs and Innovative Biomaterials in Dentistry is indispensable reading for students, researchers, and clinicians who need to stay up-to-date on the cutting-edge developments of tissue engineering and regenerative medicine applied to dental sciences.
Regenerative medicine and tissue engineering play significant roles in the treatment of currently intractable conditions, such as chronic heart failure, stroke, chronic osteoarthritis, and other maladies. Regenerative medicine and tissue engineering generally depend on the utilization of stem cells to treat patients but may also utilize mature cells that would not normally be considered as stem cells (e.g., skin). Stem cells (like mature cells) may be obtained from many sources in the body including bone marrow, cord blood, cord tissue, adipose tissue, etc. Although stem cells are often used in therapy immediately upon isolation, in many circumstances, the stem and progenitor cells will be harvested, processed and banked frozen until a later time. Biobanking is a convenient alternative to same-day therapeutic use, in that it allows for patient recovery (e.g., from liposuction), provides time to identify the best treatment options, and may allow for multiple interventions with additional patient inconvenience or risk.
Nurses are already nurse managers. They must manage patient caseloads and care plans as well as supervise aides, technicians, and other care providers. But moving from this type of organic management to a defined nurse manager role is not a natural progression. Nurse managers must command a vast, diverse, and robust skill set, and those skills must first be defined, explained, and operationalized for success. In an environment that offers new managers little support, where do they turn? The Nurse Manager’s Survival Guide (4th Ed.) provides an overview of a nurse manager’s major roles and responsibilities—all the fundamentals needed for success in one easy-to-use, consolidated, practical reference. From tips on building the right team to budgeting basics, time-management tools, and advice on taking care of one’s self (and their team), author Tina Marrelli supplies the resources nurse managers need to excel in day-to-day operations.
This book provides a comprehensive review of the recent advances in the research of systemic sclerosis (scleroderma). Systemic sclerosis is a complex autoimmune disease characterized by vasculopathy, fibrosis, and immune activation. This disease is also associated with certain susceptibility genes and is affected by epigenetic regulation. Recent studies have revealed a variety of new evidence suggestive of the pathogenesis of the disease. These include endothelial progenitor cells, cytokines and growth factors, and B cells. Studies using animal models have also provided novel insight into the pathomechanisms. In addition to these topics, the book covers clinical research regarding biomarkers and autoantibodies. This volume will benefit all rheumatologists and dermatologists as well as basic scientists, especially immunologists, molecular biologists, and biochemists.
Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine addresses the key concepts involved in the interactions between cells and biomaterials in the musculoskeletal tissue engineering and regenerative medicine field. The updated developments and challenges of the mechanisms/mechanobiology and structure-function properties of those interactions, as well as emerging technologies underlying tissue-engineered scaffolding, are carefully discussed. Lastly, cell engineering and cell-based therapies, growth factors/drugs properties, vascularization, immunomodulation are also outlined. Given the large number of musculoskeletal disorders and related inju...
Materials Science and Engineering in Food Product Development A comprehensive and accessible guide to the food development applications of cutting-edge materials science In Materials Science and Engineering in Food Product Development, distinguished researcher Wing-Fu Lai delivers an authoritative exploration of the roles played by materials science and engineering in food product development. In the book, the authors employ a practical, industrial perspective to illustrate how food products, especially functional foods, can benefit from the incorporation of materials science technologies. The book includes helpful glossary sections in each chapter, as well as important notes to highlight in...
Studies in Natural Products Chemistry, Volume 79 covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it's possible to isolate and rapidly determine the structures and biological activity of natural products. - Focuses on the chemistry of bioactive natural products - Contains contributions by leading authorities in the field - Presents sources of new pharmacophores
Genetics and Evolution of Infectious Diseases, Third Edition discusses the evolving field of infectious diseases and their continued impact on the health of populations, especially in resource-limited areas of the world where they must confront the dual burden of death and disability due to infectious and chronic illnesses. Although substantial gains have been made in public health interventions for the treatment, prevention, and control of infectious diseases, in recent decades the world has witnessed the emergence of the human immunodeficiency virus (HIV) and the COVID-19 pandemic, increasing antimicrobial resistance, and the emergence of many new bacterial, fungal, parasitic, and viral pa...