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Approaches in Integrative Bioinformatics provides a basic introduction to biological information systems, as well as guidance for the computational analysis of systems biology. This book also covers a range of issues and methods that reveal the multitude of omics data integration types and the relevance that integrative bioinformatics has today. Topics include biological data integration and manipulation, modeling and simulation of metabolic networks, transcriptomics and phenomics, and virtual cell approaches, as well as a number of applications of network biology. It helps to illustrate the value of integrative bioinformatics approaches to the life sciences. This book is intended for researchers and graduate students in the field of Bioinformatics. Professor Ming Chen is the Director of the Bioinformatics Laboratory at the College of Life Sciences, Zhejiang University, Hangzhou, China. Professor Ralf Hofestädt is the Chair of the Department of Bioinformatics and Medical Informatics, Bielefeld University, Germany.
In recent years, the ryanodine receptor has emerged as a new and very promising target for the treatment of several cardiovascular disorders, including cardiac arrhythmias and heart failure. This volume is the most current publication devoted to the major intracellular calcium-release channel, the ryanodine receptor. "In this series of brief but informative chapters, the contributions progress from the basic gene family and primary structure, through its 3D structure so far, to its regulation and physiology." David E. Clapham, MD, PhD Professor of Neurobiology and Pediatrics Harvard Medical School Dr. Xander H.T. Wehrens received his M.D. and Ph.D. degrees from Maastricht University in the N...
The premier single-volume reference in the field of anesthesia, Clinical Anesthesia is now in its Sixth Edition, with thoroughly updated coverage, a new full-color design, and a revamped art program featuring 880 full-color illustrations. More than 80 leading experts cover every aspect of contemporary perioperative medicine in one comprehensive, clinically focused, clear, concise, and accessible volume. Two new editors, Michael Cahalan, MD and M. Christine Stock, MD, join Drs. Barash, Cullen, and Stoelting for this edition. A companion Website will offer the fully searchable text, plus access to enhanced podcasts that can be viewed on your desktop or downloaded to most Apple and BlackBerry devices. This is the tablet version which does not include access to the supplemental content mentioned in the text.
The updated fourth edition of this comprehensive, highly respected reference covers all you need to know about obstetric anesthesia-from basic science to various anesthesia techniques to complications. The editorial team of leading authorities in the field now features Drs. Linda S. Polley, Lawrence C. Tsen, and Cynthia A. Wong and presents the latest on anesthesia techniques for labor and delivery and medical disorders that occur during pregnancy. This edition features two new chapters and rewritten versions of key chapters such as Epidural and Spinal Analgesia and Anesthesia. Emphasizes the treatment of the fetus and the mother as separate patients with distinct needs to ensure the applica...
Stoelting's Anesthesia and Co-existing Disease, Fourth South Asia Edition
Authors highlight several promising discoveries in the field of calcium signaling that provide new information about both genetic and acquired pathologies. Their discussions will give you new insights into the underlying causes of congenital and acquired diseases and point the way to new, even more promising research and therapies.
“Diagnostics in Plant Breeding” is systematically organizing cutting-edge research reviews on the development and application of molecular tools for the prediction of plant performance. Given its significance for mankind and the available research resources, medical sciences are leading the area of molecular diagnostics, where DNA-based risk assessments for various diseases and biomarkers to determine their onset become increasingly available. So far, most research in plant genomics has been directed towards understanding the molecular basis of biological processes or phenotypic traits. From a plant breeding perspective, however, the main interest is in predicting optimal genotypes based on molecular information for more time- and cost-efficient breeding schemes. It is anticipated that progress in plant genomics and in particular sequence technology made recently will shift the focus from “explanatory” to “predictive” in crop science. This book assembles chapters on all areas relevant to development and application of predictive molecular tools in plant breeding by leading authorties in the respective areas.
Recent advances in technology have led to the unprecedented accuracy in measurements of endogenous electric fields around sites of tissue disruption. State-of-the-art molecular approaches demonstrate the role of bioelectricity in the directionality and speed of cell migration, proliferation, apoptosis, differentiation, and orientation. New informat
Merging topical data from recently published review and research articles, as well as the knowledge and insight of industry experts, Omics Applications in Crop Science delves into plant science, and various technologies that use omics in agriculture. This book concentrates on crop breeding and environmental applications, and examines the applications of various omics technologies including genomics, transcriptomics, proteomics, metabolomics to important agronomic, horticultural, medicinal, plantation, fiber, forage, and bioenergy crops. It covers the application of omics technologies in several important crops, including cereal, and pulse. It explores the brassica species, drought tolerance ...