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RNA Interference (RNAi) technology has rapidly become one of the key methods used in functional genomics. RNAi is used to block the expression of genes and create phenotypes that can potentially yield clues about the function of these genes. In the postgenomic era, the elucidation of the physiological function of genes has become the rate-limiting step in the quest to develop 'gene-based drugs' and RNAi could potentially play a pivotal role in the validation of such novel drugs. In this overview, the basic concepts and applications of RNAi biology are discussed. Leading experts from both academia and industry have contributed to this invaluable reference. The volume is forwarded by Andrew Fire, one of the winners of the 2006 Nobel Prize for the discovery of RNA Interference.
In numerous conversations with our colleagues from India, it was suggested that we help to institute a series of symposia in India similar in nature to those that have been conducted by our Latin American colleagues for more than 10 years. We were fortunate to have with us in Oak Ridge Dr. Niyogi and Dr. Mitra from Indian universities. Their close ties with the Bose Institute in Calcutta and the resultant correspondence with the Institute Director, Dr. S. M. Sircar, provided the stimulus for organization of this first Indian symposium, which was held in Calcutta. Under the direction of Dr. Sircar, Dr. B. B. Biswas did an outstandingjob of organizing this conference. Financial support was arr...
From Physiology and Chemistry to Biochemistry features ten prominent scientists offering perspectives and insights from the fields of physiology, plant biology, microbiology, genetics, biophysics, molecular biology, immunology and biotechnology to answer questions with regard to India. They examine major discoveries, developments and research that shaped the direction of the discipline along with the research groups and institutions involved. Issues such as ethical implications of new developments in biotechnology, and practical applications of research in agriculture, medicine, forensics, industry are discussed.
First multi-year cumulation covers six years: 1965-70.
Independent India's struggle to overcome famine, hunger, and malnutrition, as told through the voices of politicians, planners, and citizens alike.
This book provides an integrated collection of timely articles on the use of bioarray techniques in the fields of biotechnology and molecular medicine. It is the first book to comprehensively integrate molecular diagnostics and molecular pathology. This book serves as an indispensable reference for graduate students, post-docs, and professors as well as an explanatory analysis for executives and scientists in biotechnology and pharmaceutical companies.
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How the debate over genetically modified crops in India is transforming science and politics Genetically modified or transgenic crops are controversial across the world. Advocates see such crops as crucial to feeding the world’s growing population; critics oppose them for pushing farmers deeper into ecological and economic distress, and for shoring up the power of agribusinesses. India leads the world in terms of the intensity of democratic engagement with transgenic crops. Anthropologist Aniket Aga excavates the genealogy of conflicts of interest and disputes over truth that animate the ongoing debate in India around the commercial release of transgenic food crops. The debate may well transform agriculture and food irreversibly in a country already witness to widespread agrarian distress, and over 300,000 suicides by farmers in the last two decades. Aga illustrates how state, science, and agrarian capitalism interact in novel ways to transform how democracy is lived and understood, and sheds light on the dynamics of technological change in populous, unequal polities.