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Proteostasis and Chaperone Surveillance
Proteostasis is central to the development of various human diseases caused due to excessive protein misfolding and the disregulation of the protein quality control system. In this book, respected researchers from many leading institutions contribute their insights on proteostasis maintenance. The coverage mainly focuses on the basics of maintaining proteostasis, the consequences of proteostatic system failure, and how chaperone systems constantly maintain proteostasis. In addition, the book presents in detail different treatment strategies for diseases caused by proteostatic system failure, as well as the inhibition of proteostatic failure using small molecule compounds. It examines advances in the modulation of proteopathies, providing a comprehensive source of key mechanistic insights on these diseases. As such, the book offers a valuable resource for beginners and more experienced investigators alike who are looking for detailed and reliable information on protein homeostasis, the diseases that can develop due to related imbalances and the essential role of molecular and chemical chaperones.
Intelligent Technologies and Applications
This book constitutes the refereed proceedings of the Second International Conference on Intelligent Technologies and Applications, INTAP 2019, held in Bahawalpur, Pakistan, in November 2019. The 60 revised full papers and 6 revised short papers presented were carefully reviewed and selected from 224 submissions. Additionally, the volume presents 1 invited paper. The papers of this volume are organized in topical sections on AI and health; sentiment analysis; intelligent applications; social media analytics; business intelligence;Natural Language Processing; information extraction; machine learning; smart systems; semantic web; decision support systems; image analysis; automated software engineering.
Systems Biology Application in Synthetic Biology
This book introduces students to methods that will help them understand behaviour in terms of cellular components and their interactions in non-intuitive ways, which calls for an interdisciplinary approach combining mathematical, chemical, computational and biological strategies. Tibor Ganti was one of the early pioneers who proposed a theoretical framework to understand living principles in terms of chemical transformation cycles and their coupling. The twenty-first century then brought with it a novel ‘systems’ paradigm, which shone new light on all previous work and was accompanied by numerous implications for the way we conceive of chemical and biological complexity today. This book ...
Memoirs of Faizabad, Being a Translation of the "Tarikh-i-Farahbakhsh" of Muhammad Faiz Bakhsh: 1782-1818
Eye-witness account of the author.
New Trends in Natural Product
Based on presentations made during the 6th International Symposium on Natural Product Chemistry, this book is divided into two broad sections. Section A includes articles on synthetic routes developed to complex natural products, while Section B is a compilation of discoveries of new natural products and their pharmacological properties. There are several chapters devoted to various advances in the ongoing quest for improved anticancer agents from natural sources, be they from plants, marine organisms or microorganisms. Approaches to the development of new antimalarial agents are reviewed, as are strategies for cancer chemopreventive agents.
Medieval and Modern India
Translation of twelve rare Urdu and Persian works.
Integral Transforms and Operational Calculus
Researches and investigations involving the theory and applications of integral transforms and operational calculus are remarkably wide-spread in many diverse areas of the mathematical, physical, chemical, engineering and statistical sciences. This Special Issue contains a total of 36 carefully-selected and peer-reviewed articles which are authored by established researchers from many countries. Included in this Special Issue are review, expository and original research articles dealing with the recent advances on the topics of integral transforms and operational calculus as well as their multidisciplinary applications
