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The definitive reference on the rational design of cell-penetrating peptides enables readers to develop tailor-made peptides for their specific needs. In recent years, cell-penetrating peptides (CPPs) have become valuable tools for the cellular delivery of proteins, nucleic acids, and drugs. These small peptide sequences can be artificially designed and synthesized with custom-made characteristics to mediate the efficient and non-toxic transport of biomolecules, drugs, or nanoparticles into the cell. Cell-Penetrating Peptides: Design, Development, and Applications provides an up-to-date account of the development and use of CPPs for delivering membrane-impermeable bioactive molecules into ce...
Organic Synthesis: State of the Art 2009-2011 is a convenient, concise reference that offers a summary of current research in organic synthesis. The fourth volume in the esteemed State of the Art series, the book complies two years' worth if Douglas Taber's popular weekly column, "Organic Chemistry Highlights." The series is an invaluable resource, leading chemists quickly and easily to the most significant developments in the field. -- Book Jacket.
Over 1 million copies sold in Japan! Young, old, made of rubber or rusty metal, anybody can do the splits. Eiko, a yoga instructor from Japan, teaches you how in just four weeks and you can achieve dramatic health benefits in the process. Most people wish they could be more flexible, or even just feel better as they get out of bed every morning. Doing the splits is seen as the epitome of flexibility, but it also has previously unrecognized, often dramatic health benefits: - Gain better circulation - Reduce the risk of joint injuries and lower back pain - Enjoy better balance - Tighten your stomach muscles and tone the legs - Improve overall flexibility So how does it work? You will start by doing two of the basic stretches every day. Then, add one new stretch to that routine every week thereafter. The routine takes no more than five minutes a day, and in just four weeks you'll be doing a perfect splits! Some people will get it sooner, others may take a little bit longer but EVERYBODY can do the splits with Eiko's help.
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Jeder kann Spagat lernen - und Herausforderungen im Leben besser meistern «Magic Cleaning» für Geist und Seele – für einen selbstbewussteren, stressfreien und achtsamen Alltag. Spagat ist nur etwas für Yogis oder Balletttänzerinnen? Mitnichten! Jeder kann Spagat lernen, ganz unabhängig von Alter oder Gelenkigkeit. Wie, das erklärt Eiko in diesem Buch. Sie zeigt praktisch und anschaulich, wie das Spagatlernen nicht nur dem Körper, sondern auch Geist und Seele hilft: Die Eigenschaften, die man dafür braucht – Demut, Disziplin, Hingabe, Achtsamkeit – sind generell erstrebenswerte Qualitäten im Leben. Durch das Spagatlernen erhalten wir Selbstbewusstsein und Zuversicht, um auch andere, scheinbar unerreichbare Dinge anzugehen. Der neue Bewusstseinstrend aus Japan.
El revolucionario programa de estiramientos de la reina de los splits, cuyos beneficios ya conocen un millón y medio de personas en Japón. Este programa de cuatro semanas reivindica los sorprendentes beneficios que tiene para la salud hacer apenas cinco minutos al día de unos estiramientos concretos llamados splits. Convertido en un fenómeno de masas en Japón, este libro, tan útil como sencillo, nos enseña a mejorar la circulación, evitar lesiones en las articulaciones, tonificar los músculos de las piernas, mejorar el equilibrio y acabar (a cualquier edad y sin importar nuestra condición física) con las molestias causadas por la rigidez muscular. Ahora, gracias a Eiko, la «reina de los splits» en Japón, podremos olvidarnos de los dolores en la parte baja de la espalda y la hinchazón de los pies, endurecer el vientre, fortalecer las articulaciones de la cadera... y muchos más. ¡Con una rutina de cinco minutos al día conseguiremos unos increíbles resultados en tan solo cuatro semanas! La crítica ha dicho... «¿La nueva Marie Kondo?» The New York Times