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Anticancer Research
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Regression Analysis for Categorical Moderators
Does the stability of personality vary by gender or ethnicity? Does a particular therapy work better to treat clients with one type of personality disorder than those with another? Providing a solution to thorny problems such as these, Aguinis shows readers how to better assess whether the relationship between two variables is moderated by group membership through the use of a statistical technique, moderated multiple regression (MMR). Clearly written, the book requires only basic knowledge of inferential statistics. It helps students, researchers, and practitioners determine whether a particular intervention is likely to yield dissimilar outcomes for members of various groups. Associated computer programs and data sets are available at the author's website (http: //mypage.iu.edu/ haguinis/mmr).
Phthalates and Cumulative Risk Assessment
People are exposed to a variety of chemicals throughout their daily lives. To protect public health, regulators use risk assessments to examine the effects of chemical exposures. This book provides guidance for assessing the risk of phthalates, chemicals found in many consumer products that have been shown to affect the development of the male reproductive system of laboratory animals. Because people are exposed to multiple phthalates and other chemicals that affect male reproductive development, a cumulative risk assessment should be conducted that evaluates the combined effects of exposure to all these chemicals. The book suggests an approach for cumulative risk assessment that can serve as a model for evaluating the health risks of other types of chemicals.
Indoor Environment
Covering the fundamentals of air-borne particles and settled dust in the indoor environment, this handy reference investigates: * relevant definitions and terminology, * characteristics, * sources, * sampling techniques and instrumentation, * exposure assessment, * monitoring methods. The result is a useful and comprehensive overview for chemists, physicists and biologists, postgraduate students, medical practitioners, occupational health professionals, building owners and managers, building, construction and air-conditioning engineers, architects, environmental lawyers, government and regulatory professionals.
DNA Repair and Cancer
DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical field. Topics include carcinogenesis as a predictive and/or prognostic biomarker for cancer therapy, nucleotide excision repair, and tumor genetics and personalized medicine. The contributions provide essential information to scientists, pharmaceutical investigators, and clinicians interested in cancer therapy.
Solidarność trwa
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Predictive Toxicology
A comprehensive overview of techniques and systems currently utilized in predictive toxicology, this reference presents an in-depth survey of strategies, algorithms, and prediction methods to select, calculate, and represent the features and properties of chemical structures in biological systems. It provides sources of high-quality toxicity data, the most important commercial and noncommercial predictive toxicology programs, and advanced technologies in computational chemistry, biology, statistics, and data mining. Predictive Toxicology explores applications that go beyond classical structure-activity relationships and discusses programs such as OncoLogic, META, MC4PC, PASS, and lazar.
Gendered Innovations in Science and Engineering
The prominent scholars featured in Gendered Innovations in Science and Engineering explore how gender analysis can profoundly enhance human knowledge in the areas of science, medicine, and engineering. Where possible, they provide concrete examples of how taking gender into account has yielded new research results and sparked creativity, opening new avenues for future research. Several government granting agencies, such as the National Institutes of Health and the European Commission, now require that requests for funding address whether, and in what sense, sex and gender are relevant to the objectives and methodologies of the research proposed, yet few research scientists or engineers know how to do gender analysis. This book begins to rectify the situation by shedding light on the how and the why.
