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Extracellular Vesicles
Extracellular vesicles (EVs) are nanoscale vesicles secreted by cells that mediate horizontal cargo transport from donor to recipient cell, thereby establishing cell-cell communication and signaling. This book provides critical information on the fundamentals of EVs, their roles in diseases like cancer, and their use in disease management. The chapters emphasize the emerging data confirming the role of EVs in the pathogenesis of diseases and discuss the scientific advances that have made it feasible to characterize and engineer EVs, leading to their use as tools in biomarker discovery and disease diagnosis, prognosis, therapeutic application, and theranostics. This volume is a valuable resource for basic biologists, translational scientists, and clinicians.
Cell Culture
Cell culture is cell cloning technology that simulates in vivo environment conditions such as asepsis, appropriate temperature, and pH as well as certain nutritional conditions to enable cells to survive, grow, reproduce, and maintain their structure and function. Cell culture can be used to grow human, animal, plant, and microbial cells. Each type of cell culture has its own characteristics and essential conditions. This book focuses on the advanced technology and applications of cell culture in the research and practice of medical and life sciences. Chapters address such topics as primary cancer cell cultures, 2D and 3D cell cultures, stem cells, nanotechnology, and more.
Pharmacogenetics
Pharmacogenetics is the study of the effects of individual genetics on drug responses. This book provides an overview of the current state of the pharmacological genetic aspects of these treatments. It discusses drugs with genetic information to support product labeling, clinical guidelines, or significant mechanical effects. Pharmacogenetic studies have also allowed us to better understand the pharmacology of medications used to treat neurologic and psychiatric disorders. This book also reviews the current state of the science and potential clinical utility of pharmacogenetic markers for these treatments. Furthermore, it highlights the in silico approach as a promising tool for further research on experimental pharmacology.
Revolutionizing Healthcare Through Artificial Intelligence and Internet of Things Applications
Medical internet of things (IoT)-based applications are being utilized in several industries and have been shown to provide significant advantages to users in critical health applications. Artificial intelligence (AI) plays a key role in the growth and success of medical IoT applications and IoT devices in the medical sector. To enhance revenue, improve competitive advantage, and increase consumer engagement, the use of AI with medical IoT should be encouraged in the healthcare and medical arena. Revolutionizing Healthcare Through Artificial Intelligence and Internet of Things Applications provides greater knowledge of how AI affects healthcare and medical efficacy in order to improve outputs. It focuses on a thorough and comprehensive introduction to machine learning. Covering topics such as patient treatment, cyber-physical systems, and telemedicine, this premier reference source is a dynamic resource for hospital administrators, medical professionals, government officials, students and faculty of higher education, librarians, researchers, and academicians.
Polymeric Biomaterials
Biomaterials include a versatile group of molecules that have been designed to interact with biological systems for various applications and polymeric biomaterials are being designed based on their availability and compatibility. This book summarizes fabrication techniques, features, usage, and promising applications of polymeric biomaterials in diversified areas including advantageous industrial applications. Each chapter exclusively covers a distinct application associated with major classes of polymeric biomaterials. Features: Provides platform related to fabrication and advancement of all categories of polymeric biomaterials Explores advancement of pertinent biomedical and drug delivery systems Includes wide range of biomaterials and its application in diversified fields Gives out environmental justification of green biopolymers and their applications in water remediation Discusses advanced applications of bio-composite polymers viz. food packaging and anti-corrosive coatings This book is aimed at researchers in Polymer Sciences, Biomaterials, Chemical/Bio Engineering, Materials Chemistry, and Biotechnology.
Nanoparticles in Cancer Theranostics
This book comprehensively reviews the application of nanoparticles in cancer diagnosis and treatment. The introductory section provides a fundamental understanding of cancer biology, its global incidence and prevalence, and the intricate nano–bio interactions at the cellular level. The subsequent section discusses the pivotal role of nanoparticles in precise cancer detection, enhancing cancer imaging and serving as contrast agents for accurate diagnosis. It also presents cutting-edge nanotechnology-based methods for detecting HTLV-1 retroviruses. The following section covers the utilization of lipid-based nanoparticles, monoclonal antibodies, and advanced nanotherapeutics for targeted cancer treatments. This book is a useful resource for researchers, clinicians, and students in the fields of oncology and nanotechnology.
For Blood and Money: Billionaires, Biotech, and the Quest for a Blockbuster Drug
"A master class in the machinations of modern drug development." —Adrian Woolfson, Science A gripping business narrative and scientific thriller about what it takes to bring a wonder drug to market—and save countless lives. For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug, and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time. In the multibillion-dollar b...
