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Virus Bioinformatics
Virus bioinformatics is evolving and succeeding as an area of research in its own right, representing the interface of virology and computer science. Bioinformatic approaches to investigate viral infections and outbreaks have become central to virology research, and have been successfully used to detect, control, and treat infections of humans and animals. As part of the Third Annual Meeting of the European Virus Bioinformatics Center (EVBC), we have published this Special Issue on Virus Bioinformatics.
Handbook of RNA Biochemistry
The second edition of a highly acclaimed handbook and ready reference. Unmatched in its breadth and quality, around 100 specialists from all over the world share their up-to-date expertise and experiences, including hundreds of protocols, complete with explanations, and hitherto unpublished troubleshooting hints. They cover all modern techniques for the handling, analysis and modification of RNAs and their complexes with proteins. Throughout, they bear the practising bench scientist in mind, providing quick and reliable access to a plethora of solutions for practical questions of RNA research, ranging from simple to highly complex. This broad scope allows the treatment of specialized methods side by side with basic biochemical techniques, making the book a real treasure trove for every researcher experimenting with RNA.
RNA Infrastructure and Networks
RNAs form complexes with proteins and other RNAs. The RNA‐infrastructure represents the spatiotemporal interaction of these proteins and RNAs in a cell‐wide network. RNA Infrastructure and Networks brings together these ideas to illustrate the scope of RNA‐based biology, and how connecting RNA mechanisms is a powerful tool to investigate regulatory pathways. This book is but a taste of the wide range of RNA‐based mechanisms that connect in the RNA infrastructure.
Evolutionary Genomics and Systems Biology
A comprehensive, authoritative look at an emergent area in post-genomic science, Evolutionary genomics is an up-and-coming, complex field that attempts to explain the biocomplexity of the living world. Evolutionary Genomics and Systems Biology is the first full-length book to blend established and emerging concepts in bioinformatics, evolution, genomics, and structural biology, with the integrative views of network and systems biology. Three key aspects of evolutionary genomics and systems biology are covered in clear detail: the study of genomic history, i.e., understanding organismal evolution at the genomic level; the study of macromolecular complements, which encompasses the evolution of...
Viral Fitness and Evolution
This book unifies general concepts of plant and animal virus evolution and covers a broad range of topics related to theoretical and experimental aspects of virus population dynamics and viral fitness. Timely topics such as viral mechanisms to cope with antiviral agents, the adaptability of the virus to new hosts, emergence of new viral phenotypes, and the connections between short- and long-term virus evolution are included. By comparing plant and animal viruses, universal mechanisms responsible for fitness variations, viral emergence and disease mechanisms are explored. Although emphasis is put on specific plant and human viral pathogens, relevant similarities and differences to other viruses are highlighted. Additionally, readers will learn more about the adaptability of coronaviruses, including the recently emerged SARS-CoV-2, the causative agent of the COVID-19 pandemic. The book is aimed at students and scientists interested in basic and applied aspects of plant and animal virus population dynamics and evolution.
Bioinformatics Research and Applications
This book constitutes the refereed proceedings of the 9th International Symposium on Bioinformatics Research and Applications, ISBRA 2013, held in Charlotte, NC, USA, in May 2013. The 25 revised full papers presented together with 4 invited talks were carefully reviewed and selected from 46 submissions. The papers cover a wide range of biomedical databases and data integration, high-performance bio-computing, biomolecular imaging, high-throughput sequencing data analysis, bio-ontologies, molecular evolution, comparative genomics and phylogenomics, molecular modeling and simulation, pattern discovery and classification, computational proteomics, population genetics, data mining and visualization, software tools and applications.
Computers and Games
This book constitutes the thoroughly refereed post-conference proceedings of the 9th International Conference on Computers and Games, CG 2016, held in Leiden, The Netherlands,in conjunction with the 19th Computer Olympiad and the 22nd World Computer-Chess Championship. The 20 papers presented were carefully reviewed and selected of 30 submitted papers. The 20 papers cover a wide range of computer games and many different research topics in four main classes which determined the order of publication: Monte Carlo Tree Search (MCTS) and its enhancements (seven papers), concrete games (seven papers), theoretical aspects and complexity (five papers) and cognition model (one paper). The paper Using Partial Tablebases in Breakthrough by Andrew Isaac and Richard Lorentz received the Best Paper Award.
Introduction to Molecular Genomics
Introduction to Molecular Genomics introduces the college student to the fundamental concepts of molecular biology and genomics. The text puts an emphasis on important topics in the subject that contribute to the learner’s understanding. These topics include molecular genomics, biodiversity and molecular phenomenon behind evolution of species, modern molecular methods for enhanced genomics research, DNA modifications at the molecular level for transgenic animal species, the role of cell environment on the gene expression, to name a few. The book has been designed to suit the requirements of educational courses in molecular biology, genomics and biochemistry. Key features - Covers basic concepts on key topics in molecular biology and genomics - Simple easy-to-read layout - Includes references for further reading - Includes a section on ethical aspects of scientific research Introduction to Molecular Genomics is a simple primer for students in applied or advanced life science courses at undergraduate levels
Evolutionary Computation in Combinatorial Optimization
This book constitutes the refereed proceedings of the 19th European Conference on Evolutionary Computation in Combinatorial Optimization, EvoCOP 2019, held as part of Evo* 2019, in Leipzig, Germany, in April 2019, co-located with the Evo* 2019 events EuroGP, EvoMUSART and EvoApplications. The 14 revised full papers presented were carefully reviewed and selected from 37 submissions. The papers cover a wide spectrum of topics, ranging from the foundations of evolutionary computation algorithms and other search heuristics to their accurate design and application to both single- and multi-objective combinatorial optimization problems. Fundamental and methodological aspects deal with runtime analysis, the structural properties of fitness landscapes, the study of metaheuristics core components, the clever design of their search principles, and their careful selection and configuration. Applications cover domains such as scheduling, routing, partitioning and general graph problems.
Genetic Programming
This book constitutes the refereed proceedings of the 22nd European Conference on Genetic Programming, EuroGP 2019, held as part of Evo* 2019, in Leipzig, Germany, in April 2019, co-located with the Evo* events EvoCOP, EvoMUSART, and EvoApplications. The 12 revised full papers and 6 short papers presented in this volume were carefully reviewed and selected from 36 submissions. They cover a wide range of topics and reflect the current state of research in the field. With a special focus on real-world applications in 2019, the papers are devoted to topics such as the test data design in software engineering, fault detection and classification of induction motors, digital circuit design, mosquito abundance prediction, machine learning and cryptographic function design.
