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Interleukin-10 in Health and Disease
This volume provides a set of reviews dedicated to the biology of Interleukin (IL)-10. It includes chapters on its importance for maintaining immune homeostasis in humans, its role in intestinal immunity and its functions during viral and bacterial infections. In addition, it presents reviews on the mechanisms linking innate microbial recognition to the production of IL-10 and on how IL-10 recognition by its receptor functions. The roles of T and B cells as relevant sources of IL-10 are also discussed, with an emphasis on the clinical opportunities offered by IL-10-producing Tr1 cells for the suppression of unwanted immunity. Finally, the functions of other cytokines of the IL-10 family are presented. Collectively, these articles provide a comprehensive overview of our current knowledge on one of the most important anti-inflammatory cytokines known to date.
Regulatory T Cells and Clinical Application
Covering one of the hottest topics in immunology today, this book provides a comprehensive view of all types of regulatory T cells described so far in the literature. The book will have broad appeal to both researchers and clinicians.
The Islets of Langerhans
When new fellows join my lab, I give them some reading materials so that they can orient themselves in their assignment in a new eld. When fellows leave my lab, some after writing their dissertations, I prefer to give them a book as a symbolic present. I was longing for a book that contained something on more or less eve- thing about the islets. At the same time, I wished it contained information as recent as possible. There are a few such books in the market but they are pretty outdated. I started picking islets myself from October 1990, when I joined the Rolf Luft Center, Karolinska Institutet. Over the years my fascination for islet research remained high. Since last year, I felt a strong...
Oral Tolerance
This brings three areas together to continue to promote the expansion of knowledge in the area; the explosion in understanding the potential mechanisms of oral tolerance through the use of mouse models, a greater appreciation for the existence of novel regulatory T cells, and a clearer view of the way in which the mucosal immune system responds.
Edifici rustici romani tra pianura e Appennino. Stato della ricerca
L’Oltrepò pavese in generale, la Valle Staffora in particolare, hanno un enorme potenziale informativo per quel che riguarda l’assetto del territorio in antico. Mai però era stato approntato un programma organico di ricerca fino a oggi. I numerosi interventi archeologici operati in quelle terre sono stati generalmente frutto del controllo attento del territorio da parte della Soprintendenza, prevalentemente attraverso interventi di emergenza, derivati da lavori edili o agricoli. Un unico pur ridotto precedente di indagine programmata è rappresentato dalle campagne di scavo in loc. Casette di Campospinoso (PV), negli anni 2005-2008, curato dallo scrivente per l’Università di Pavia. ...
Regulatory T Cells
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