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Practical Medical Oncology Textbook
This textbook combines essential information on clinical cancer medicine with a guide to the latest advances in molecular oncology and tumor biology. Providing a systematic overview of all types of solid tumors, including epidemiology and cancer prevention, genetic aspects of hereditary cancers, differential diagnosis, typical signs and symptoms, diagnostic strategies and staging, and treatment modalities, it also discusses new and innovative cancer treatments, particularly targeted therapy and immunotherapy. Expert commentaries at the end of each chapter highlight key points, offer insights, suggest further reading and discuss clinical application using case descriptions. This textbook is an invaluable, practice-oriented tool for medical students just beginning their clinical oncology studies, as well as for medical oncology residents and young professionals.
Retinoids
This volume contains papers presented at the Conference on Retinoids: New Trends in Research and Clinical Applications, held in 1991 in Palermo, Italy, describing the latest research findings on biochemistry, nutrition, molecular and cell biology and developmental biology, as well as the pharmacology and the therapeutic use of vitamin A and its congeners.;Written by leading authorities in the field from the USA, Europe and Japan, Retinoids, amongst other things: addresses retinol-supported retinoic acid (RA) synthesis and catabolism; identifies synthetic ligands with a high selective affinity for RAR-alpha, -beta and -gamma nuclear receptors, determining if they would show pharmacological properties similar to the natural parent substance all-trans RA; considers the embryonic/foetal cellular retinoid-binding proteins and evidence for their participation in normal and abnormal morphogenesis; discusses a novel arotinoid, Ro 40-8757, that exhibited improved anti-tumour efficacy and safety in pre-clinical tests; and reports the audioradiographic distribution of retinol and RA in organs of pregnant hamsters and foetuses.
The Novel Coronavirus
This volume discusses the ecology, evolution and pandemic of the coronavirus, as well as its psychosocial, environmental and economic impact. It also offers a general view of the epidemiology, pathogenesis, control and prevention of the coronavirus, while highlighting the global challenge, future threats and clinical management of COVID-19. It also provides insights into biochemistry and laboratory diagnosis. The book will be an excellent resource for clinicians, policymakers, government departments and civil society organizations alike.
Dietary and Supplement Strategies for the Prevention and Treatment of Metabolic Syndrome
Metabolic syndrome (MetS) afflicts about 20-30 % of the global population, and is increasing in prevalence and incidence. MetS is linked to an unhealthy lifestyle (e.g. low physical activity and unbalanced and western-style diets), which leads to a low-grade inflammatory state and an increase in oxidative stress, due to an unbalanced ratio of pro-oxidants and antioxidant species in the human body. This low-grade inflammatory state triggers cytokine hypersecretion and eventually leads to insulin resistance which aggravates the major components of this syndrome such as hypertension, dyslipidemia, and abdominal obesity in a vicious cycle. This is a critical clinical problem because it leads the patient to have a greater risk of developing type 2 diabetes with progression to cerebrovascular and endothelial pathologies.
COVID-19 and Communities
This volume presents an interdisciplinary reflection on the SARS-COV-2 pandemic and its consequences elaborated in real-time. It embodies the University of Palermo’s values and mission by bringing together academics of very diverse disciplinary fields on an issue that is disrupting all aspects of individual and community existence. This volume captures the voices of academics during the pandemic, allowing to crystallize the discourses that are emerging in a wide variety of scientific fields as events unfold and knowledge is rapidly evolving. They share the belief that to shed adequate light on the complex and multifaceted phenomenon of the COVID-19 pandemic and its consequences necessarily...
Retinoids: From Basic Science to Clinical Applications
Basic investigators as well as clinicians will find this volume valuable both as a summary of recent research and as a stimulus for future experimental work in this continuously expanding field.
Neuroscience Letters
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Der lange Atem
Die oft leistungsentscheidende Bedeutung von Atmung und Atemstörungen wird im Sport vielfach unterschätzt. Dieses Buch zeigt Ihnen, wie Sport-Atemphysiotherapie mittels Prophylaxe, Therapie und Eigenbehandlung das "Gesamtsystem Athlet" wirksam unterstützen kann – bei Profis wie bei Amateursportlern. Vorgestellt werden: - Die anatomischen und physiologischen Grundlagen der Atmung - Die häufigsten Atemwegserkrankungen und funktionellen Atemwegsstörungen, insbesondere bei Sportlern - Ursachen und Entstehungsmechanismen von Atemstörungen, die gerade im Sport besondere Auswirkungen haben - Vorbeugende und therapeutische Maßnahmen - mit speziellem Augenmerk auf den Sport- und Wettkampfbereich - Maßnahmen der Eigenbehandlung – von Schleimhautpflege über regelmäßige Atemübungen bis hin zu Yoga. Athleten, Trainer, (Physio-)Therapeuten, Betreuer und Ärzte finden in diesem Buch alles, um den "langen Atem" des Sportlers zu fördern. Das Buch eignet sich für: - Freizeit- und Profisportler*innen - Trainer*innen und Betreuer*innen - Physiotherapeut*innen - Ärzt*innen
