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GENOME EDITING IN DRUG DISCOVERY A practical guide for researchers and professionals applying genome editing techniques to drug discovery In Genome Editing in Drug Discovery, a team of distinguished biologists delivers a comprehensive exploration of genome editing in the drug discovery process, with coverage of the technology’s history, current issues and techniques, and future perspectives and research directions. The book discusses techniques for disease modeling, target identification with CRISPR, safety studies, therapeutic editing, and intellectual property issues. The safety and efficacy of drugs and new target discovery, as well as next-generation therapeutics are also presented. Of...
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Discover the wonders of this captivating region with Cadogan's classic guidebook: the medieval glories of Lucca and San Gimignano, the Renaissance charms and murky Medici decadence of Florence, the wine routes of Chianti, Siena's frenzied Palio horse race, the hill towns, Pisa's Leaning Tower-all set against Tuscany's golden landscapes, coastline and islands.
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The AACR Annual Meeting is a must-attend event for cancer researchers and the broader cancer community. This year's theme, "Delivering Cures Through Cancer Science," reinforces the inextricable link between research and advances in patient care. The theme will be evident throughout the meeting as the latest, most exciting discoveries are presented in every area of cancer research. There will be a number of presentations that include exciting new data from cutting-edge clinical trials as well as companion presentations that spotlight the science behind the trials and implications for delivering improved care to patients. This book contains abstracts 1-2696 presented on April 17-18, 2016, at the AACR Annual Meeting.
Als eine der wichtigsten Institutionen der geistlichen Musik blickt die Cappella Giulia der Petersbasilika auf eine fünfhundertjährige Geschichte zurück. Giancarlo Rostirolla lässt diese wechselvolle und faszinierende Geschichte anhand von Originaldokumenten aus der Bibliothek der Päpste und aus den Archiven des Kapitels von San Pietro in Vaticano lebendig werden. In der Cappella Giulia, 1513 von Papst Julius II. gegründet, wirkten die bedeutendsten Repräsentanten der römischen Vokalpolyphonie: allen voran Giovanni Animuccia und Giovanni Pierluigi da Palestrina, Francesco Soriano, Virgilio Mazzocchi, Orazio Benevoli, Paolo Lorenzani und Pietro Bencini, aber auch Opernkomponisten wie ...
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