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Systems Biology is concerned with the quantitative study of complex biosystems at the molecular, cellular, tissue, and systems scales. Its focus is on the function of the system as a whole, rather than on individual parts. This exciting new arena applies mathematical modeling and engineering methods to the study of biological systems. This book is the first of its kind to focus on the newly emerging field of systems biology with an emphasis on computational approaches. The work covers new concepts, methods for information storage, mining and knowledge extraction, reverse engineering of gene and metabolic networks, as well as modelling and simulation of multi-cellular systems. Central themes include strategies for predicting biological properties and methods for elucidating structure-function relationships.
This book constitutes the thoroughly refereed post-conference proceedings of the 14th International Meeting on Computational. Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2017, held in Cagliari, Italy, in September 2017. The 19 revised full papers presented were carefully reviewed and selected from 44 submissions. The papers deal with the application of computational intelligence to open problems in bioinformatics, biostatistics, systems and synthetic biology, medical informatics, computational approaches to life sciences in general.
This book constitutes the refereed proceedings of the International Workshop on Computational Methods in Systems Biology, CMSB 2003, held in Rovereto, Italy, in February 2003. The 11 revised full papers presented together with 2 invited papers, 7 position papers, and 11 abstracts were carefully reviewed and selected from 30 submissions. Among the topics addressed are modeling languages for systems biology, concurrency in biological systems, constraint programming, logical methods in systems biology, formal methods for the analysis of biomolecular systems, quantitative analysis of biomolecular systems, and simulation and modeling techniques for systems biology.
This highly interdisciplinary book, covering more than six fields, from philosophy and sciences all the way up to the humanities and with contributions from eminent authors, addresses the interplay between content and context, reductionism and holism and their meeting point: the notion of emergence. Much of today’s science is reductionist (bottom-up); in other words, behaviour on one level is explained by reducing it to components on a lower level. Chemistry is reduced to atoms, ecosystems are explained in terms of DNA and proteins, etc. This approach fails quickly since we can’t cannot extrapolate to the properties of atoms solely from Schrödinger's equation, nor figure out protein fol...
This book constitutes the refereed proceedings of the 9th International Conference on High Performance Computing, HiPC 2002, held in Bangalore, India in December 2002. The 57 revised full contributed papers and 9 invited papers presented together with various keynote abstracts were carefully reviewed and selected from 145 submissions. The papers are organized in topical sections on algorithms, architecture, systems software, networks, mobile computing and databases, applications, scientific computation, embedded systems, and biocomputing.
Beginning with art and architecture and culminating with science and mathematics itself, this book discusses geometric ideas and their many applications throughout history. These range from ancient to modern, concrete to abstract, and familiar to cutting edge. Each chapter is written by a leading expert or pioneer in their own field, and the book should be a valuable resource for students and teachers of geometry alike.
This book constitutes the revised selected papers of the 9th Italian Workshop on Advances in Artificial Life and Evolutionary Computation held in Vietri sul Mare, Italy, in May 2014, in conjunction with the 24th Italian Workshop on Neural Networks, WIRN 2014. The 16 papers presented have been thoroughly reviewed and selected from 40 submissions. They cover the following topics: artificial neural networks; fuzzy inference systems; rough set; approximate reasoning; and optimization methods such as evolutionary computation, swarm intelligence, particle swarm optimization.
This book constitutes the refereed proceedings of the 6th Conference on Computability in Europe, CiE 2010, held in Ponta Delgada, Azores, Portugal, in June/July 2010. The 28 revised papers presented together with 20 invited lectures were carefully reviewed and selected from 90 submissions. The papers address not only the more established lines of research of computational complexity and the interplay between proofs and computation, but also novel views that rely on physical and biological processes and models to find new ways of tackling computations and improving their efficiency.
This book constitutes the revised selected papers of the 13th Italian Workshop on Artificial Life and Evolutionary Computation, WIVACE 2018, held in Parma, Italy, in September 2018. The 12 full papers presented were thoroughly reviewed and selected from 30 submissions. They cover the following topics: Boolean networks and complex systems; economic, societal and technological applications; chemical, biological and medical applications. The chapter “Unveiling Latent Relations in the Photonics Techno-Economic Complex System” is open access under a CC BY 4.0 license at link.springer.com.
This book constitutes the refereed proceedings of the 16th Italian Workshop on Artificial Life and Evolutionary Computation, WIVACE 2022, held in Gaeta, Italy, during September 14–16, 2022. The 21 full papers and 3 short papers included in this book were carefully reviewed and selected from 45 submissions. They were organized in topical sections as follows: answer set programming; networks and complex systems, metaheuristics, robotics, and machine learning Chapters 7, 8, and 9 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.