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Radiotherapy (RT) is a cornerstone of cancer treatment, being routinely used for approximately half of cancer patients in high-income countries. Despite the extensive use of RT for over 60 years, its toxicity on normal tissues often limits the treatment of radioresistant tumors and is responsible for significant decrease in patient’s quality of life. However, it was recently established that ultra-high dose rate (UHDR) irradiation induces significantly less normal tissues toxicities, while keeping similar antitumor effect compared to conventional dose rate irradiation. This so called “FLASH Effect" was demonstrated in vivo on different animal models and different organs by delivering the total amount of radiation dose in a very short time ( usually <200 ms), with average dose rates above 40 Gy/s and with different particles including electrons, protons and photons.
This open access book addresses the pressing need for sustainability in urban development and the use of technology, with cities to serve as the main stage for strategies that seek to meet the targets and the cross-sector priorities indicated in the EU’s Next Generation program, all in pursuit of a solid recovery on the part of the European economy, along lines of ecological transition, digitalization, competitiveness, training, and inclusion to overcome social, territorial, and gender differences. The international study encounter is meant to promote visions shared by architectural technology and other disciplines, which, though they may appear to differ, are closely interconnected, with the aim of achieving an open, interdisciplinary integration capable of proposing concrete projects regarding topics held to be of strategic importance to the future of the built environment. These are identified to draw up evolving scenarios of architecture and cities suited to reflection, at various levels, on innovative models of process and product.
This book presents the latest key research into the performance and reliability aspects of dependable fault-tolerant systems and features commentary on the fields studied by Prof. Kishor S. Trivedi during his distinguished career. Analyzing system evaluation as a fundamental tenet in the design of modern systems, this book uses performance and dependability as common measures and covers novel ideas, methods, algorithms, techniques, and tools for the in-depth study of the performance and reliability aspects of dependable fault-tolerant systems. It identifies the current challenges that designers and practitioners must face in order to ensure the reliability, availability, and performance of s...
This book is an introduction to techniques and applications of optical methods for materials Characterization in civil and environmental engineering. Emphasizing chemical sensing and diagnostics, it is written for students and researchers studying the physical and chemical processes in manmade or natural materials. Optical Phenomenology and Applications - Health Monitoring for Infrastructure Materials and the Environment, describes the utility of optical-sensing technologies in applications that include monitoring of transport processes and reaction chemistries in materials of the infrastructure and the subsurface environment. Many of the applications reviewed will address long standing issu...
This volume, a product of the first Tricontinental Conference organized by Yeditepe University, İstanbul, brings together perspectives on democracy and development in Africa, the Middle East and Latin America. Representing local voices and insight, the contributors here respond to the dearth of comparative analysis on these three regions. In spite of the differences observed in colonial practices and postcolonial transitions, a shared disenchantment with the performance of competitive politics comes to the forefront in these geographical areas. Decades after decolonization, low-intensity democracy and the continuing potential for democratic reversals and backsliding make the study of these three regions relevant. Considering the debates on protests, social upheavals, activism, change and continuity, this book encourages the reader to survey the various trials and tribulations of the postcolonial era.
Technological evolutions have changed the field of architecture exponentially, leading to more stable and energy-efficient building structures. Architects and engineers must be prepared to further enhance their knowledge in the field in order to effectively meet new and advancing standards. Architecture and Design: Breakthroughs in Research and Practice is an authoritative resource for the latest research on the application of new technologies and digital tools that revolutionize the work of architects globally, aiding in architectural design, planning, implementation, and restoration. Highlighting a range of pertinent topics such as design anthropology, digital preservation, and 3D modeling, this publication is an ideal reference source for researchers, scholars, IT professionals, engineers, architects, contractors, and academicians seeking current research on the development and creation of architectural design.
This book gathers the peer-reviewed papers presented at the 13th International Conference on Structural Analysis of Historical Constructions (SAHC), held in Kyoto, Japan, on September 12-15, 2023. It highlights the latest advances and innovations in the field of conservation and restoration of historical and heritage structures. The conference topics encompass history of construction and building technology, theory and practice of conservation, inspection methods, non-destructive techniques and laboratory testing, numerical modeling and structural analysis, management of heritage structures and conservation strategies, structural health monitoring, repair and strengthening strategies and tec...
This book provides a detailed overview of multifunctional sensors, covering discussions on different types of multifunctional sensors developed in past years. As a case study, the development of admittance-type multifunctional sensors is provided, constituting its construction, working principles, measurements, and instrumentation used. It also explores a review of the research in the field from 1990 to 2022. It will be a useful resource for researchers of sensor technologies across physics, engineering, and other physical sciences. Key Features • Presents a case study of a multifunctional sensor that measures temperature and level simultaneously. • Discusses latest trends in the area and can be understood by advanced students up to research level scholars. • Looks ahead to the future of these sensors for further research opportunities.
'a vital resource' TLS 'Compelling collection' Literary Review The Reformation was a seismic event in history whose consequences are still unfolding in Europe and across the world. Martin Luther's protests against the marketing of indulgences in 1517 were part of a long-standing pattern of calls for reform in the Christian Church. But they rapidly took a radical and unexpected turn, engulfing first Germany, and then Europe, in furious arguments about how God's will was to be 'saved'. However, these debates did not remain confined to a narrow sphere of theology. They came to reshape politics and international relations; social, cultural, and artistic developments; relations between the sexes;...