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S. Kobayashi M. Ueno T. Kitanosono Bismuth Catalysts in Aqueous Media Y. Matano Pentavalent Organobismuth Reagents in Organic Synthesis: Alkylation, Alcohol Oxidation and Cationic Photopolymerization S. W. Krabbe R. S. Mohan Environmentally Friendly Organic Synthesis Using Bismuth(III) Compounds T. Ollevier Bismuth-Catalyzed Addition of Silyl Nucleophiles to Carbonyl Compounds and Imines M. Rueping B. J. Nachtsheim Bismuth Salts in Catalytic Alkylation Reactions J. A. R. Salvador S. M. Silvestre R. M. A. Pinto R. C. Santos C. Le Roux New Applications for Bismuth(III) Salts in Organic Synthesis: From Bulk Chemicals to Steroid and Terpene Chemistry S. Matsunaga M. Shibasaki Cationic Bismuth-Catalyzed Hydroamination and Direct Substitution of the Hydroxy Group in Alcohols with Amides S. Shimada M. L. N. Rao Transition-Metal Catalyzed C–C Bond Formation Using Organobismuth Compounds J. S. Yadav A. Antony B.V. S. ReddyBismuth(III) Salts as Synthetic Tools in Organic Transformations
Introduction to Fragment-Based Drug Discovery, by Daniel A. Erlanson Fragment Screening Using X-Ray Crystallography, by Thomas G. Davies and Ian J. Tickle Hsp90 Inhibitors and Drugs from Fragment and Virtual Screening, by Stephen Roughley, Lisa Wright, Paul Brough, Andrew Massey and Roderick E. Hubbard Combining NMR and X-ray Crystallography in Fragment-Based Drug Discovery: Discovery of Highly Potent and Selective BACE-1 Inhibitors, by Daniel F. Wyss, Yu-Sen Wang, Hugh L. Eaton, Corey Strickland, Johannes H. Voigt, Zhaoning Zhu and Andrew W. Stamford Combining Biophysical Screening and X-Ray Crystallography for Fragment-Based Drug Discovery, by Michael Hennig, Armin Ruf and Walter Huber Targeting Protein–Protein Interactions and Fragment-Based Drug Discovery, by Eugene Valkov, Tim Sharpe, May Marsh, Sandra Greive and Marko Hyvönen Fragment Screening and HIV Therapeutics, by Joseph D. Bauman, Disha Patel and Eddy Arnold Fragment-Based Approaches and Computer-Aided Drug Discovery, by Didier Rognan
This book is testimony to the degree of advancement in the research and development of sensors in Italy. It covers the typical areas of sensors and microsystems, such as chemical and biological sensors, physical sensors, optical sensors and micromechanics.As in previous proceedings of the Italian Conference on Sensors and Microsystems, a section of this book is devoted to advanced sensor applications. The book focuses on the development of sensors for the human body, and the relationship between human bodies and sensor systems.
Porphyrins, phthalocyanines and their numerous analogs and derivatives are materials of tremendous importance in chemistry, materials science, physics, biology and medicine. They are the red color in blood (heme) and the green in leaves (chlorophyll); they are also excellent ligands that can coordinate with almost every metal in the Periodic Table. Grounded in natural systems, porphyrins are incredibly versatile and can be modified in many ways; each new modification yields derivatives, demonstrating new chemistry, physics and biology, with a vast array of medicinal and technical applications.As porphyrins are currently employed as platforms for study of theoretical principles and applicatio...
This is the seventh set of Handbook of Porphyrin Science.Porphyrins, phthalocyanines and their numerous analogue and derivatives are materials of tremendous importance in chemistry, materials science, physics, biology and medicine. They are the red color in blood (heme) and the green in leaves (chlorophyll); they are also excellent ligands that can coordinate with almost every metal in the Periodic Table. Grounded in natural systems, porphyrins are incredibly versatile and can be modified in many ways; each new modification yields derivatives, demonstrating new chemistry, physics and biology, with a vast array of medicinal and technical applications.As porphyrins are currently employed as pl...
This is the sixth set of Handbook of Porphyrin Science.This 5-volume set provides a comprehensive review of the most up-to-date research on porphyrin, heme and chlorophyll biochemistry, as well as applications to biomedicine and bio-inspired energy. In-depth coverage of topics along with perspectives on outstanding questions and future research directions by the authors make these volumes an essential resource for both beginning and advanced investigators in the field. It is also suitable for non-experts in porphyrin, who wish to have an overview of the fundamental discoveries and breakthroughs in the porphyrin arena related to medicine and bio-inspired energy.Bringing together the biochemistry of porphyrin-binding proteins and their clinical relevance and applications to medicine and renewable energy, this set provides readers with an integrated coverage of porphyrin biochemistry. At the same time, it challenges readers with new questions and perspectives of research regarding the role of porphyrin biochemistry in the future of medicine and renewable energy.
In our constantly plugged-in and connected world, image is everything. People, groups, organizations, and countries frequently come under suspicion of wrongdoing and sometimes require defense. Accounts, Excuses, and Apologies describes the image-repair strategies that may be used to help defuse these threats. The Third Edition of this classic book builds on theories for rehabilitating a damaged reputation by adding two new forms of denial: straw denial (appearing to deny an accusation by sidestepping it) and deflecting attention (trying to get the audience to focus on something other than the accusations against you). Five contexts for image repair are examined: corporate, political, sports/entertainment, international, and third party (when one person or organization tries to repair the image of another). The book’s case studies include current instances of reputation repair, including Vladimir Putin on Ukraine and President Joe Biden on Afghanistan; Southwest Airlines on flight cancellations; Kobe Bryant on accusations of rape; and Donald Trump on the January 6 hearings.
This book explores the role of surface effects in optical phenomena in nanoscience, from two different perspectives. When systems are reduced in volume, the ratio of surface versus volume increases. At the level of single nanostructures this translates into an enhanced role of interfacial chemistry and thermodynamics. At the level of systems of nanostructures, it translates into larger density on interfaces, which in turn leads to such intriguing collective effects as plasmonics or multiple reflection and refraction phenomena. The book highlights both perspectives presenting sample applications. Without claiming to be exhaustive, the book aims to stimulate readers in this potentially rewarding field.
Armed–Disarmed Effects in Carbohydrate Chemistry: History, Synthetic and Mechanistic Studies, by Bert Fraser-Reid and J. Cristóbal López * A Survey of Ley’s Reactivity Tuning in Oligosaccharide Synthesis, by Ana M. Gómez * “Active–Latent” Thioglycosyl Donors and Acceptors in Oligosaccharide Syntheses, by Tze Chieh Shiao and René Roy * Effect of Electron-Withdrawing Protecting Groups at Remote Positions of Donors on Glycosylation Stereochemistry, by Kwan Soo Kim and Dae-Hwan Suk * Influence of Protecting Groups on the Reactivity and Selectivity of Glycosylation: Chemistry of the 4,6-O-Benzylidene Protected Mannopyranosyl Donors and Related Species, by Sylvain Aubry, Kaname Sasaki, Indrajeet Sharma and David Crich * Superarmed and Superdisarmed Building Blocks in Expeditious Oligosaccharide Synthesis, by Hemali D. Premathilake and Alexei V. Demchenko * Programmable One-Pot Glycosylation, by Chung -Yi Wu and Chi -Huey Wong * Uronic Acids in Oligosaccharide and Glycoconjugate Synthesis, by Jeroen D. C. Codée, Alphert E. Christina, Marthe T. C. Walvoort, Herman S. Overkleeft and Gijsbert A. van der Marel
How an acceptance of our limitations can lead to a more fulfilling life and a more harmonious society We live in a world oriented toward greatness, one in which we feel compelled to be among the wealthiest, most powerful, and most famous. This book explains why no one truly benefits from this competitive social order, and reveals how another way of life is possible—a good-enough life for all. Avram Alpert shows how our obsession with greatness results in stress and anxiety, damage to our relationships, widespread political and economic inequality, and destruction of the natural world. He describes how to move beyond greatness to create a society in which everyone flourishes. By competing l...