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Databases have revolutionized nearly every aspect of our lives. Information of all sorts is being collected on a massive scale, from Google to Facebook and well beyond. But as the amount of information in databases explodes, we are forced to reassess our ideas about what knowledge is, how it is produced, to whom it belongs, and who can be credited for producing it. Every scientist working today draws on databases to produce scientific knowledge. Databases have become more common than microscopes, voltmeters, and test tubes, and the increasing amount of data has led to major changes in research practices and profound reflections on the proper professional roles of data producers, collectors, ...
What are the conditions that foster true novelty and allow visionaries to set their eyes on unknown horizons? What have been the challenges that have spawned new innovations, and how have they shaped modern biology? In Dreamers, Visionaries, and Revolutionaries in the Life Sciences, editors Oren Harman and Michael R. Dietrich explore these questions through the lives of eighteen exemplary biologists who had grand and often radical ideas that went far beyond the run-of-the-mill science of their peers. From the Frenchman Jean-Baptiste Lamarck, who coined the word “biology” in the early nineteenth century, to the American James Lovelock, for whom the Earth is a living, breathing organism, t...
The Face of AIDS film archive at Karolinska Institutet, Sweden, consists of more than 700 hours of unedited and edited footage, shot over a period of more than thirty years and all over the world by filmmaker and journalist Staffan Hildebrand. The material documents the HIV/AIDS pandemic and includes scenes from conferences and rallies, and interviews with activists, physicians, people with the infection, and researchers. It represents a global historical development from the early years of the AIDS crisis to a situation in which it is possible to live a normal life with the HIV virus. This volume brings together a range of academic perspectives – from media and film studies, medical histo...
TEXTBOOK OF VON WILLEBRAND DISEASE Comprehensive resource summarizing recent research on von Willebrand disease, showing clinicians how to optimize management of patients with this disorder The newly revised and updated second edition of Textbook of von Willebrand Disease: Basic and Clinical Aspects, 2nd edition describes the important and complex role of von Willebrand factor (VWF) in hemostasis and thrombosis, covering not only the current understanding of its molecular biology, but also the association between genetic variants of VWF and different von Willebrand disease (VWD) phenotypes. The text also reviews the important area of the obstetric and gynecological manifestations of VWD, as ...
Von Willebrand Disease: Basic and Clinical Aspects provides an insight into all aspects of the condition. Since its discovery, von Willebrand disease has been extensively studied and the causative factor deficiency, the understanding of the condition and its treatment has greatly improved. This book summarizes recent research and will help to optimize the management of patients with von Willebrand disease. This valuable book describes the important and complex role of von Willebrand factor in hemostasis and thrombosis. In addition to the current understanding of its molecular biology, this book gives particular focus to the association between genetic variants of von Willebrand factor and di...
Jan Waldenström (1906-1996) was the leading Swedish internist of the twentieth century. The first chapter of the book presents his remarkable family including five generations of physicians. Born in Stockholm, we follow JW to medical school at Uppsala University during 1924–33. In 1934–5, he spent a year in the laboratory of Nobel Laureate Hans Fischer in Munich. In 1937, he defended a landmark thesis on acute intermittent porphyria. As “Docent” (assistant professor) in Uppsala, he discovered two new diseases in 1943. In 1944–5, he spent 7 months in the US commissioned by the Swedish Health Board. This started friendships with leading colleagues and scientists. With time, JW foste...
Thrombotic and bleeding disorders affect at least 10 million people in the US alone. As a result there has been much more interest and research into this field. The field of haematology is undergoing major advances in thrombosis research, including significant additions to recommended treatment protocols and guidelines. This new handbook will cover all aspects of the practical mangement of commonly encountered thrombotic and bleeding disorders, with emphasis on clinical diagnosis, treatment and day-to-day management. It will distil the most clinically relevant material from the literature for all those working in the field of haemostasis and thrombosis.
This book is the latest volume in the highly successful series Comprehensive Biochemistry. It provides a historical and autobiographical perspective of the developments in the field through the contributions of leading individuals who reflect on their careers and their impact on biochemistry. Volume 45 is essential reading for everyone from graduate student to professor, placing in context major advances not only in biochemical terms but in relation to historical and social developments. Readers will be delighted by the lively style and the insight into the lives and careers of leading scientists of their time.* Contributors are distinguished scientists in the field * Unique series of personal recollections * Presents scientific research in a historical perspective
Since 1952, postgraduate courses for practising physicians and speci alists have been given by the Medical Faculty of the University of Leiden in the Boerhaave Quarter, in which most of its clinics and laboratories are located. During these years, recent advances in a wide variety of m~dical fields and subjects have been discussed by distin guished speakers from many countries. The steadily increasing atten dance has shown that, as could be expected from the rapid progress of modern medicine, there is a widely felt need for this form of postgra duate study. In 1957, therefore, the Leiden Medical Faculty appointed a permanent committee for the organization of postgraduate medical education. O...