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Success comes in many forms and in synthesis it can be a failure that results in their ultimate successful solutions. This long-awaited sequel to "Dead Ends and Detours" retains the proven concept while featuring over 20 new case studies of failed strategies and their (successful) solutions in natural product total synthesis. Additionally, computational models are used to discuss the problem in much more detail and to provide readers with additional information not found in the primary literature. The topics range from classic synthetic reactions (e.g. Diels Alder reaction), metal-mediated coupling reactions, metathesis, and asymmetric catalysis to the importance of protecting and activating groups. This book will benefit not only graduate students in organic chemistry but also advanced researchers as they gain knowledge derived from the step-by-step analysis of mistakes made in the past and, thus be able to improve their own chemical reaction planning. With its coverage of the most commonly applied reaction types, the book perfectly complements its predecessor, which focuses on general aspects, such as reactivity and selectivity.
Northern Spain is miles away - both literally and figuratively - from the crowded resorts of the southern coast. This cluster of ancient kingdoms is home Gothic cathedrals, stunning mountain ranges, charming seaside towns and the buzzing cultural capital of Bilbao. From sampling fresh seafood and delicious cider to walking the medieval pilgrim route to Santiago - Footprint's 6th edition of the Northern Spain Handbook will help you make the most of your trip. • In-depth coverage of the region's activities, from climbing to skiing • Highlight maps to help you get the best from this vast region • Exceptional background and history section - from the Reconquista, to pilgrims, to politics • Where to stay and eat for your budget; also offers information on the best refugios, paradores and sidrerías • Includes feature on the Camino de Santiago Packed with valuable information on this fascinating area of Europe, Footprint’s Northern Spain Handbook will ensure that you get the best out of this culturally rich destination.
Directory of foreign diplomatic officers in Washington.
The Lloyd's Register of Shipping records the details of merchant vessels over 100 gross tonnes, which are self-propelled and sea-going, regardless of classification. Before the time, only those vessels classed by Lloyd's Register were listed. Vessels are listed alphabetically by their current name.
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.