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Apoptosis is a highly regulated mechanism by which cells undergo cell death in an active way. As one of the most challenging tasks concerning cancer is to induce apoptosis in malignant cells, researchers increasingly focus on natural products to modulate apoptotic signaling pathways. This book reviews the main effects of natural compounds on the different apoptotic signaling pathways, including the intrinsic and extrinsic apoptosis pathways, the NF-kB-mediated pathway, the PI3K/Akt signaling, and other main pathways. Among the topic specially covered are: Effects of natural compounds on cancer cells Natural compounds as inducers of cell death Diet in health and disease Inflammation and cance...
Meeting the desire for a comprehensive book that collects and curates the vast amount of knowledge gained in the field of singlet oxygen, this title covers the physical, chemical and biological properties of this reactive oxygen species and also its increasingly important applications across chemical, environmental and biomedical areas.The editors have a long and distinguished background in the field of singlet oxygen chemistry and biomedical applications, giving them a unique insight and ensuring the contributions attain the highest scientific level.The book provides an up to date reference resource for both the beginner and experienced researcher and crucially for those working across disciplines such as photochemistry, photobiology and photomedicine.
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Keynote speakers at the cell signaling meeting in Luxembourg have provided chapters on hypoxia signal transduction, phosphoserine/threonine-binding domains, targeting of polycomb repressive complexes, conserved signaling mechanisms in innate immunity, and signal transduction by stress-activated MAP kinases. Other topics included among these reports on recent research are receptor signaling, protein kinase cascades as therapeutic targets, cell death in cancer, inflammation-specific signaling, cell signaling pathways leading to regulated chromatin modifications, and transcriptional control. The chapters have been published in four volumes (Part A to D), offering a comprehensive overview about ...
Keynote speakers at the cell signaling meeting in Luxembourg have provided chapters on hypoxia signal transduction, phosphoserine/threonine-binding domains, targeting of polycomb repressive complexes, conserved signaling mechanisms in innate immunity, and signal transduction by stress-activated MAP kinases. Other topics included among these reports on recent research are receptor signaling, protein kinase cascades as therapeutic targets, cell death in cancer, inflammation-specific signaling, cell signaling pathways leading to regulated chromatin modifications, and transcriptional control. The chapters have been published in four volumes (Part A to D), offering a comprehensive overview about ...
Thin Film Coatings for Biomaterials and Biomedical Applications discusses the latest information on coatings, including their historic use by scientists who are looking to improve the properties and biological responses of the material-host interface. Thin films, in particular, are becoming more widely researched and used as an alternative to traditional sprayed coatings because they have a more uniform structure and therefore greater stability. This book provides readers with a comprehensive guide to thin film coatings and their application in the biomaterials field. Part One of the book details the fundamentals of thin films for biomedical application, while Part Two looks at the special properties of thin films, with a final section reviewing functional thin films and their usage in biomedical applications. - Provides a comprehensive review on the fundamentals, properties, and functions of thin film coatings for biomaterials - Covers a broad range of applications for implantable biomaterials - Written by an international team of contributors who carefully tailor the presented information in a way that addresses industry needs
The second edition of Microbiology of Waterborne Diseases describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. The book is divided into sections covering bacteria, protozoa, and viruses. Other sections detail methods for detecting and identifying waterborne microorganisms, and the ways in which they are removed from water, including chlorine, ozone, and ultraviolet disinfection. The second edition of this handbook has been updated with information on biofilms and antimicrobial resistance. The impact of global warming and climate change phenomena on waterborne illnesses are also discussed. This book serves as an indispen...
As a scientific discipline, photochemistry generates more than 1200 articles and reviews a year across a range of fields. Keeping up with the literature can be difficult, but Specialist Periodical Reports present an informed view of the latest thinking and research in the field. The latest and 42nd volume in the series has a special emphasis on organic and computational aspects of photochemistry, drawn from the literature published in 2012 and 2013. Several chapters are devoted to comprehensive and critical reviews of various organic compounds and functional groups. One chapter is devoted to photoclick chemistry, another on continuous flow photochemical reactions. New methods for excited state energies and properties are also examined, as are new approaches to singlet oxygen photosensitisation in biological media and functions containing a heteroatom different from oxygen. Photochemistry provides essential reading for anyone wishing to keep up to date with the literature or gain a broad appreciation of the field.
The conclusion to Penelope Green's bestselling trilogy about her life in Italy that includes When in Rome and See Naples and Die From her rooftop terrace, Penelope looks out across the sparkling waters of the Bay of Naples, and into a garden of lemon trees and magnolias. Has her Italian dream come true? Imagine catching a ferry home and stepping onto a waterfront lined with multicoloured buildings, busy with fishing boats and couples strolling to their favourite café. For Penny and her Italian love Alfonso, the idyllic island of Procida can offer the life they are looking for. But first Penny has to find a way into its small community. One thing she has in common with the locals is a love o...