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Sex and Gender Differences in Alzheimer's Disease: The Women's Brain Project offers for the first time a critical overview of the evidence documenting sex and gender differences in Alzheimer's disease neurobiology, biomarkers, clinical presentation, treatment, clinical trials and their outcomes, and socioeconomic impact on both patients and caregivers. This knowledge is crucial for clinical development, digital health solutions, as well as social and psychological support to Alzheimer's disease families, in the frame of a precision medicine approach to Alzheimer's disease.This book brings together up-to-date findings from a variety of experts, covering basic neuroscience, epidemiology, diagn...
The book explores the intricate connections between the nervous and immune systems in the context of neurodegenerative disorders, offering a comprehensive overview of the bidirectional communication between these systems and their implications for disease progression and therapeutic interventions. The book aims to understand the recent developments in the field of neuroimmune communication. Key Features: In-depth analysis of immunological biomarkers and therapeutic targets for neurodegenerative disorders. Exploration of the role of glial cells in neuroimmune interactions and their dual nature in disease pathology. Examination of short- and long-range interactions between the central nervous ...
Research and innovation are integral parts of the global response to dementia. Yet, the Global status report on the public health response to dementia shows that despite some encouraging efforts most countries are far from reaching the adopted targets of the Global action plan on the public health response to dementia 2017–2025. This blueprint for dementia research summarizes the current state of dementia research across six broad themes, identifies existing knowledge gaps, and outlines 15 strategic goals with actions and timebound milestones to address these gaps. The blueprint also outlines drivers of research that together create an enabling research environment that is essential for accelerating dementia research globally. Going forward, the blueprint will guide policymakers, funders, and the research community on future activities in dementia research, and contribute to making dementia research more efficient, equitable, and impactful.
International Review on Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. - Provides the authority and expertise of leading contributors from an international board of authors - Presents the latest release in International Review on Neurobiology serials - Updated release includes the latest information on Sex and Gender Differences in Neurological Disease
Sex Differences in Neurology and Psychiatry, Volume 175, addresses this important issue by viewing major neurological and psychiatric conditions through the lens of sexual dimorphism, providing an entirely novel approach to understanding vulnerability factors, as well as potential new treatment strategies in several common neuropsychiatric disorders. The handbook comprises four major sections: (1) Introduction to sex differences in neuroanatomy and neurophysiology, (2) Description of the impact of genetic, epigenetic, sex hormonal and other environmental effects on cerebral sex dimorphism, (3) Review of sex differences in neurologic disorders, and (4) Review of sex differences in psychiatric disorders. - Explores sex differences in human neuroanatomy and neurophysiology - Offers a pathway toward a gender-specific treatment of neurologic and psychiatric disorders - Provides an overview of the genetics of sex hormones, human brain structure, and function, as well as the epigenetics, environment and social context
Recent research on Neurodegenerative disorders such as Alzheimer's Disease, Parkinson's Disease, etc. and Neuropsychiatric disorders such as Schizophrenia, has shown strong evidence that altered brain tissue structure, physiology, and connectivity reflect the extent of severity of behavioral and physical abnormalities. With the advancement of high field strength MR technologies like MRS (Magnetic Resonance Spectroscopy), fMRI (functional Magnetic Resonance Imaging) and DTI (Diffusion Tensor Imaging), it has become possible to non-invasively measure these changes brain microenvironment in terms of levels of antioxidants; neurotransmitters; regional activity, susceptibility and connectivity du...
With hopelessness at unprecedented levels around the world, and a key predictor of suicide, violence, self-harm, and addiction, it is essential to teach the ‘how’ of hope. The Biggest Little Book About Hope teaches the hope skills necessary for anyone looking to integrate hope into their everyday lives.