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A iniciação científica no ensino médio: novos olhares sobre as linguagens surgiu a partir da necessidade que os professores pesquisadores do GELIF (Grupo de Estudos em Linguagens do IFPE) sentiram de propiciar aos seus orientandos do PIBIC a oportunidade de publicarem as pesquisas que desenvolveram entre durante a pandemia de COVID-19. A obra contempla as mais diversas correntes teórico-metodológicas da área de linguagens e traz trabalhos que enveredam pela teoria literária, pela crítica de cinema, pelo dialogismo bakhtiniano, pela semiótica greimasiana, pela Análise Crítica do Discurso etc.
Phytotherapy Approaches for Treatment of Mouth Ulcers is a book with updated and illustrated text with pictures and graphs that help to define, characterize and classify mouth ulcers. The most frequent oral mucosa lesions are the aphthous ulcerations with a prevalence of 4.6 to 30.6%. These can be defined as a fundamental lesion characterized by the absence of the epithelial tissue layer, which makes the subjacent conjunctive tissue unprotected and vulnerable to external aggressions. There are three main forms, the most common being the aphthous; these are small, rounded, defined ulcerations that are painful and heal in 10 to 14 days. The other form of recurrent aphthous ulceration is the ty...
This expansive and practical textbook contains organic chemistry experiments for teaching in the laboratory at the undergraduate level covering a range of functional group transformations and key organic reactions.The editorial team have collected contributions from around the world and standardized them for publication. Each experiment will explore a modern chemistry scenario, such as: sustainable chemistry; application in the pharmaceutical industry; catalysis and material sciences, to name a few. All the experiments will be complemented with a set of questions to challenge the students and a section for the instructors, concerning the results obtained and advice on getting the best outcome from the experiment. A section covering practical aspects with tips and advice for the instructors, together with the results obtained in the laboratory by students, has been compiled for each experiment. Targeted at professors and lecturers in chemistry, this useful text will provide up to date experiments putting the science into context for the students.
The main focus of the book is the geological and geophysical interpretation of sedimentary basins along the South, Central and North Atlantic conjugate margins, but concepts derived from physical models, outcrop analogues and present-day margins are also discussed in some chapters. There is an encompassing description of several conjugate margins worldwide, based on recent geophysical and geological datasets. An overview of important aspects related to the geodynamic development and petroleum geology of Atlantic-type sedimentary basins is also included. Several chapters analyse genetic mechanisms and break-up processes associated with rift-phase structures and salt tectonics, providing a full description of conjugate margin basins based on deep seismic profiles and potential field methods.--
The Atlantic Forest is one of the 36 hotspots for biodiversity conservation worldwide. It is a unique, large biome (more than 3000 km in latitude; 2500 in longitude), marked by high biodiversity, high degree of endemic species and, at the same time, extremely threatened. Approximately 70% of the Brazilian population lives in the area of this biome, which makes the conflict between biodiversity conservation and the sustainability of the human population a relevant issue. This book aims to cover: 1) the historical characterization and geographic variation of the biome; 2) the distribution of the diversity of some relevant taxa; 3) the main threats to biodiversity, and 4) possible opportunities to ensure the biodiversity conservation, and the economic and social sustainability. Also, it is hoped that this book can be useful for those involved in the development of public policies aimed at the conservation of this important global biome.
Leishmaniases are a group of tropical diseases that affect millions of people worldwide. They are considered neglected diseases prevalent in emerging countries in Latin America, West Africa, and Southeast Asia and still occurring in Mediterranean countries. There is no human vaccine available to prevent and control the disease infection. For the last 70 years, the available chemotherapy has been constituted by first-line (pentavalent antimonials) and second-line drugs (amphotericin B, pentamidine, paramomycin, and miltefosine). Its route of administration is difficult, the treatment is long, and its efficiency varies depending on the parasite species and clinical manifestations, which results in the emergence of resistant cases. Moreover, they present high toxicity to patients, and even some less toxic formulations available, are still expensive for the poorest countries’ vulnerable populations. This often leads to abandonment and failure of treatment. The medical-scientific community is facing difficulties to overcome these issues with new suitable therapies, and the identification of new drug targets. So, it means that efforts to identify new strategies must continue.
This book, which can be used as a text for teaching purposes, gives a fascinating, and authoritative treatment both the rights protected by the Inter-American system and of the way in which its institutions work. An important part of the book is a thorough, article by article account of the guarantee in the American Declaration of the Rights and Duties of Man and in the American Convention on Human Rights of civil, political, economic, social and cultural rights in the light of the jurisprudence of the Inter-American Commission on Human Rights and the Inter-American Court of Human Rights, and of the Commission's many country reports on the human rights situation in particular states. There are also chapters on the rights of indigenous peoples, amnesty laws and states of emergencies. The evolution and current methods of work of the Commission and the Court are set out at length and their achievements are critically assessed. The role of non-governmental organisations is also examined in this context. The book will be invaluable to all those interested in the protection of human rights in the Americas and international human rights law generally.
The five volume set LNCS 10960 until 10964 constitutes the refereed proceedings of the 18th International Conference on Computational Science and Its Applications, ICCSA 2018, held in Melbourne, Australia, in July 2018. Apart from the general tracks, ICCSA 2018 also includes 34 international workshops in various areas of computational sciences, ranging from computational science technologies, to specific areas of computational sciences, such as computer graphics and virtual reality. The total of 265 full papers and 10 short papers presented in the 5-volume proceedings set of ICCSA 2018, were carefully reviewed and selected from 892 submissions.
Mammalian cell lines command an effective monopoly for the production of therapeutic proteins that require post-translational modifications. This unique advantage outweighs the costs associated with mammalian cell culture, which are far grater in terms of development time and manufacturing when compared to microbial culture. The development of cell lines has undergone several advances over the years, essentially to meet the requirement to cut the time and costs associated with using such a complex hosts as production platforms. This book provides a comprehensive guide to the methodology involved in the development of cell lines and the cell engineering approach that can be employed to enhanc...