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Ocular Pharmacology: Recent Breakthroughs and Unmet Needs
The research on ocular pharmacology has increased significantly, over the past decade. More recently, the discovery and approval of eye disease modifying treatments is considered an unbelievable scientific breakthrough. Anti-VEGF molecules, cell therapy and gene therapy for age-related retinal degeneration, autologous corneal cells replacement, and Leber’s congenital amaurosis to name a few as some impressive examples. New drugs have been recently introduced for the treatment of glaucoma focusing on new pharmacological targets, such as Rho kinase inhibitors. For example, such novel treatments have been approved for optic neuromyelitis spectrum disorders. Regarding diseases of the front of ...
Chronic Inflammation and Neurodegeneration in Retinal Disease
We would like to acknowledge and thank Francesco Petrillo, Carlo Gesualdo, Chiara Bianca Maria Platania and Maria Consiglia Trottafor their support on the collection’s Editorial article.
Data Driven Science for Clinically Actionable Knowledge in Diseases
Data-driven science has become a major decision-making aid for the diagnosis and treatment of disease. Computational and visual analytics enables effective exploration and sense making of large and complex data through the deployment of appropriate data science methods, meaningful visualisation and human-information interaction. This edited volume covers state-of-the-art theory, method, models, design, evaluation and applications in computational and visual analytics in desktop, mobile and immersive environments for analysing biomedical and health data. The book is focused on data-driven integral analysis, including computational methods and visual analytics practices and solutions for discovering actionable knowledge in support of clinical actions in real environments. By studying how data and visual analytics have been implemented into the healthcare domain, the book demonstrates how analytics influences the domain through improving decision making, specifying diagnostics, selecting the best treatments and generating clinical certainty.
Diagnosis and Management of Ocular Motility Disorders
This comprehensive, clinically-grounded textbook, now in its fourth edition, supports orthoptists and ophthalmologists in decision-making through the patient care process, from presentation to discharge. Written by authors with extensive experience in teaching and research, Diagnosis and Management of Ocular Motility Disorders offers a clear and practical overview of assessment and management principles and further explores the clinical features of specific disorders, from amblyopia and infantile strabismus to supranuclear and infranuclear disorders, as well as other miscellaneous disorders of ocular movement. A brand new chapter on congenital cranial dysinnervation disorders reflects recent advances in gene mapping and increased understanding of this condition, and a new appendix provides surgical dose tables for easy reference. Now in full colour throughout, with additional diagrams and photographs of surgical techniques, this remains the key reference text for orthoptic and ophthalmic professionals managing patients with eye movement disorders.
Self Portrait in Green
'NDiaye is a hypnotic storyteller with an unflinching understanding of the rock-bottom reality of most people's life.' New York Times ' One of France's most exciting prose stylists.' The Guardian. Obsessed by her encounters with the mysterious green women, and haunted by the Garonne River, a nameless narrator seeks them out in La Roele, Paris, Marseille, and Ouagadougou. Each encounter reveals different aspects of the women; real or imagined, dead or alive, seductive or suicidal, driving the narrator deeper into her obsession, in this unsettling exploration of identity, memory and paranoia. Self Portrait in Green is the multi-prize winning, Marie NDiaye's brilliant subversion of the memoir. Written in diary entries, with lyrical prose and dreamlike imagery, we start with and return to the river, which mirrors the narrative by posing more questions than it answers.
