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A biography that traces the origins and emergence of global communication through the life and career of Guglielmo Marconi, inventor of the radio.
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This book analyzes all aspects of metronomic chemotherapy, a new approach involving low-dose, long-term, and frequently administered therapy that has preclinical and clinical activity in various tumors. After an opening section on the pharmacological bases of metronomic chemotherapy, including its antiangiogenic effects and impact on immunity, preclinical studies on various classes of drug are discussed. Clinical applications of metronomic chemotherapy in a wide variety of tumors are then addressed in detail, with description of the results of all published studies. The clinical pharmacology of metronomic chemotherapy is also considered in depth, encompassing pharmacokinetics, pharmacogenetics, pharmacoeconomics, and adverse drug reactions. The book closes by describing the role of this therapy in the veterinarian clinic.
Volume 2 of Theaters and Public Sphere in a Global and Digital Society presents several qualitative and quantitative researches on the social roles of the theatre and performance, as organized institutions or social groups, in contemporary society.
This volume is put together in honor of a distinguished historian of science, Kostas Gavroglu, whose work has won international acclaim, and has been pivotal in establishing the discipline of history of science in Greece, its consolidation in other countries of the European Periphery, and the constructive dialogue of these emerging communities with an extended community of international scholars. The papers in the volume reflect Gavroglu’s broad range of intellectual interests and touch upon significant themes in recent history and philosophy of science. They include topics in the history of modern physical sciences, science and technology in the European periphery, integrated history and philosophy of science, historiographical considerations, and intersections with the history of mathematics, technology and contemporary issues. They are authored by eminent scholars whose academic and personal trajectories crossed with Gavroglu’s. The book will interest historians and philosophers of science and technology alike, as well as science studies scholars, and generally readers interested in the role of the sciences in the past in various geographical contexts.
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In this study Donna Jo Napoli takes a common-sense approach to the notions of argument and predicate. Discussions of predication within Government and Binding theory have stressed the configurational properties of the phrases involved, and Napoli argues that this has led to proposals for more and more elaborate syntactic structures that nevertheless fail to provide genuinely explanatory accounts. She presents a convincing case for viewing the notion of predicate as a semantic primitive which cannot be defined by looking simply at the lexicon or simply at the syntactic structure, and offers a theory or predication where the key to the subject-predicate relationship is theta-role assignment. The book then goes on to offer principles for the coindexing of a predicate with its subject role player. These coindexing principles make use of Chomsky's 1986 notion of barriers, but instead of being sensitive to configurational notions like c-command and governing category, Napoli argues that they are sensitive to thematic structure. In the final chapter of the book Napoli extends the principles for predication coindexing to anaphor binding, by introducing the notion of argument ladders.
This book discusses basics of brain diseases and the role of nanobiotechnology in existing treatment options for neurodegenerative disorders. It begins with an overview of brain diseases and the need for novel drug-delivery approaches. It highlights the current route for the intranasal advanced drug-delivery systems for brain diseases. It also discusses innovative categories of drug-delivery systems, including mesoporous silica nanoparticles, polymeric nanocarriers, and lipid-based nanocarriers through multi-responsive DDSs and their implications in brain disorders. Features: Includes an overview of brain diseases and highlights the need for novel drug-delivery approaches Focuses on theoreti...