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The structural features responsible for the immunogenicity of certain parts of native protein molecules have been of interest to immunochemists and protein chemists for over three decades. Following the early work of Land steiner in 1942, which showed that peptide fragments from silk fibroin exhibited an inhibitory activity toward the reaction of the protein with its antibodies, fragments from many other protein systems have been isolated and studied. However, no concerted effort was (or could be) devoted to the elucidation of the complete antigenic structure of a protein. In order for these endeavors to be successful and meaningful, knowledge of both the amino acid sequence and the detailed...
Monthly, with annual cumulation. Recurring bibliography from MEDLARS data base. Index medicus format. Entries arranged under subject, review, and author sections. Subject, author indexes.
This comprehensive, user-friendly introductory textbook to political psychology explores the psychological origins of political behavior. The authors introduce readers to a broad range of theories, concepts, and case studies of political activity to illustrate that behavior. The book examines many patterns of political behaviors, including leadership, group behavior, voting, race, ethnicity, nationalism, terrorism, war, and genocide. It explores some of the most horrific things people do to one another for political purposes, as well as how to prevent and resolve conflict -- and how to recover from it. The goal is to help the reader understand the enormous complexity of human behavior and th...
Fibrinolysis in Disease reviews the state of the art of basic and clincal aspects of the fibrinolytic enzyme system. The text, authored by outstanding and internationally known investigators, is presented in two books. The Malignant Process, Interventions in Thrombogenic Mechanisms, and Novel Treatment Modalities discuses the molecular biology of the system's key components and their fundamental roles in a variety of thrombotic and metabolic disorders. Molecular and Hemovascular Aspects of Fybrinolysis presents the latest findings and concepts of the association between plasminogen activator (u-PA) overexpression and abnormal growth regulation in a variety of solid tumors and in leukemia. One chapter deals with various successful interventions in thrombogenic mechanisms, ranging from exercise and diet to anticoagulants and direct and indirect thrombolytic agents. It concludes with a projection of exciting, novel treatment modalities in thrombotic and malignant diseases.
Advances in Cancer Research