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Markus Heller
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Small Molecule — Protein Interactions
Based on the international workshop on 'Small Molecule - Protein Interactions' held in Berlin, April 24-26, 2002, researchers from industry and academic laboratories describe novel and efficient ways selecting promising new drug targets and developing small molecule inhibitors against them. The structure of the book corresponds to the different aspects of the drug discovery process. All chapters are written by leading experts in the field, who present and discuss the most recent state-of-the-art tools and techniques for the development of novel drugs. The value of the book lies in surveying and summarizing the approaches taken by different companies and institutions giving the reader a balanced view on the use of the latest techniques on the one hand and experience-based assistance in selecting appropriate tools for their own work on the other hand.
Highlights from Frontiers in Bioengineering and Biotechnology in 2020
Frontiers in Bioengineering and Biotechnology has evolved to become an established go-to open access publishing option for multidisciplinary bioengineering and biotechnology research and in the process has grown considerably over the last few years achieving our first Journal Impact Factor 2018 in 2019. Here we are pleased to introduce this special eBook entitled ‘Highlights from Frontiers in Bioengineering and Biotechnology in 2020’ edited by our 10 Specialty Chief Editors of Frontiers in Bioengineering and Biotechnology aiming to support Frontiers’ strong community by recognizing highly deserving authors. The work presented here highlights the broad diversity of exciting research per...
Applications of Graph Transformations with Industrial Relevance
This book constitutes the thoroughly refereed post-proceedings of the Second International Workshop on Applications of Graph Transformations with Industrial Relevance, AGTIVE 2003, held in Charlotesville, Virginia, USA in September/October 2003. The 27 revised full papers and 11 revised demo papers presented together with 2 invited papers and 5 workshop reports were carefully selected during iterated rounds of reviewing and revision. The papers are organized in topical sections on Web applications; data structures and data bases; engineering applications; agent-oriented and functional programs and distribution; object- and aspect-oriented systems; natural languages: processing and structuring; reengineering; reuse and integration; modeling languages; bioinformatics; and multimedia, picture, and visual languages.
BioNMR in Drug Research
The vast progress made in the investigation of biomolecules using NMR has only recently been rewarded with the Nobel Prize for Kurt Wüthrich. Edited by a former coworker of Wüthrich, this book presents the theoretical background on NMR of biomolecules, plus the use of NMR techniques in determining the structures of proteins and nucleic acids. BioNMR spectroscopy offers a universal tool for examining the binding of an active substance to its target protein. Its use thereby benefits the rational development of drugs. This interaction can now be investigated in a hitherto unparalleled precision and displayed in 3D - an important prerequisite for the targeted development of new active substances. The latest methods for characterizing substance-receptor complexes are demonstrated backed by many case studies from pharmaceutical research. Thus it comes as no surprise that a large number of the authors are working for leading pharmaceutical companies. With its successful mixture of basic information and application strategies, coupled with many real-life examples, this is an invaluable guide for both NMR spectroscopists and pharmaceutical researchers.
Business System Management and Engineering
The next generation of Business Process Management (BPM) methods and tools will support the development of a new generation of service-enabled applications that change and evolve over time. The trend is moving from relatively stable, organization-specific applications to dynamic ones supporting business processes. This book is an outcome of the International Workshop on Business System Management and Engineering (BSME 2010), held in Malaga, Spain, in June/July 2010, in conjunction with the TOOLS 2010 federated conferences and under the aegis of the EU Network of Excellence on Service Software and Systems (S-Cube). The goal of the workshop was to bring together experts in the fields of business process management, service-oriented architectures, and service security to discuss the current state of research and identify new issues, challenges, and research directions. The results of these discussions are reflected in this book.
Handbook of Service Description
The Handbook of Service Description introduces an in-depth overview of service description efforts. The book also highlights the recent Unified Service Description Language (USDL) in detail and discusses its methods. The Handbook of Service Description is the normative scientific reference for the upcoming standardization of the Unified Service Description Language (USDL). Complete documentation is included. The Handbook of Service Description is designed for those working in the service science industry as a reference book. Advanced-level students focused on computer science, engineering and business will also find this book a valuable asset.
Modelling Foundations and Applications
This book constitutes the proceedings of the 9th European Conference on Modelling Foundations and applications, ECMFA 2013, held in Montpellier, France, in July 2013. The 15 papers presented in this volume were carefully reviewed and selected from 51 submissions. They are on all aspects of MDE, including topics such as model querying, consistency checking, model transformation; and model-based systems engineering and domain-specific modeling.
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