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This book constitutes the thoroughly refereed post-proceedings of the Second International Workshop on Applications of Graph Transformations with Industrial Relevance, AGTIVE 2003, held in Charlotesville, Virginia, USA in September/October 2003. The 27 revised full papers and 11 revised demo papers presented together with 2 invited papers and 5 workshop reports were carefully selected during iterated rounds of reviewing and revision. The papers are organized in topical sections on Web applications; data structures and data bases; engineering applications; agent-oriented and functional programs and distribution; object- and aspect-oriented systems; natural languages: processing and structuring; reengineering; reuse and integration; modeling languages; bioinformatics; and multimedia, picture, and visual languages.
Based on the international workshop on 'Small Molecule - Protein Interactions' held in Berlin, April 24-26, 2002, researchers from industry and academic laboratories describe novel and efficient ways selecting promising new drug targets and developing small molecule inhibitors against them. The structure of the book corresponds to the different aspects of the drug discovery process. All chapters are written by leading experts in the field, who present and discuss the most recent state-of-the-art tools and techniques for the development of novel drugs. The value of the book lies in surveying and summarizing the approaches taken by different companies and institutions giving the reader a balanced view on the use of the latest techniques on the one hand and experience-based assistance in selecting appropriate tools for their own work on the other hand.
Frontiers in Bioengineering and Biotechnology has evolved to become an established go-to open access publishing option for multidisciplinary bioengineering and biotechnology research and in the process has grown considerably over the last few years achieving our first Journal Impact Factor 2018 in 2019. Here we are pleased to introduce this special eBook entitled ‘Highlights from Frontiers in Bioengineering and Biotechnology in 2020’ edited by our 10 Specialty Chief Editors of Frontiers in Bioengineering and Biotechnology aiming to support Frontiers’ strong community by recognizing highly deserving authors. The work presented here highlights the broad diversity of exciting research per...
Segmentation of anatomical structures in medical image data is an essential task in clinical practice. Dagmar Kainmueller introduces methods for accurate fully automatic segmentation of anatomical structures in 3D medical image data. The author’s core methodological contribution is a novel deformation model that overcomes limitations of state-of-the-art Deformable Surface approaches, hence allowing for accurate segmentation of tip- and ridge-shaped features of anatomical structures. As for practical contributions, she proposes application-specific segmentation pipelines for a range of anatomical structures, together with thorough evaluations of segmentation accuracy on clinical image data. As compared to related work, these fully automatic pipelines allow for highly accurate segmentation of benchmark image data.
Provides a broad sample of current information processing applications Includes examples of successful applications that will encourage practitioners to apply the techniques described in the book to real-life problems
In this work, Ken Safir develops a comprehensive theory on the role of anaphora in syntax. First, he contends that the complementary distribution of forms that support the anaphoric readings is not accidental, contrary to most current thinking, but rather should be derived from a principle, one that he proposes in the form of an algorithm. Secondly, he maintains that dependent identity relations are always possible where they are not prohibited by a constraint. Lastly, he proposes that there are no parameters of anaphora - that all anaphora-specific principles are universal, and that the patterns of anaphora across languages arise entirely from a restricted set of lexical properties. This comprehensive consideration of anaphora redirects current thinking on the subject.
This festschrift volume, published in honor of Manfred Nagl on the occasion of his 65th birthday, contains 30 refereed contributions, that cover graph transformations, software architectures and reengineering, embedded systems engineering, and more.
More and more historical texts are becoming available in digital form. Digitization of paper documents is motivated by the aim of preserving cultural heritage and making it more accessible, both to laypeople and scholars. As digital images cannot be searched for text, digitization projects increasingly strive to create digital text, which can be searched and otherwise automatically processed, in addition to facsimiles. Indeed, the emerging field of digital humanities heavily relies on the availability of digital text for its studies. Together with the increasing availability of historical texts in digital form, there is a growing interest in applying natural language processing (NLP) methods...