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The Pancreas
The PANCREAS The newest edition of the essential guide to pancreatic medicine The fourth edition of The Pancreas: An Integrated Textbook of Basic Science, Medicine, and Surgery integrates the cutting-edge research of recent years to update its presentation of this fast-growing subject. It details every known disorder of the pancreas, grounding them in a thorough understanding of pancreatic function, enhanced with high quality illustration and graphs. It also includes step-by-step guidance for relevant endoscopic techniques and surgical procedures. The Pancreas readers will also find: New comprehensive insights into three pancreatic diseases: autoimmune pancreatitis, cystic neoplasms, and neuroendocrine tumors An editorial team with decades of clinical and research experience in the US, Europe, and Asia Over 500 downloadable illustrations for use in scientific presentations The Pancreas is a foundational reference for clinicians and researchers in gastroenterology and gastrointestinal surgery.
Translational Pancreatic Cancer Research
This book incorporates a multi-disciplinary approach to present how research results can be translated into clinical trials. The first part begins with a chapter on variants of pancreatic cancer, precursor lesions and groups of people at risk to developing the disease. There is a particular focus on intraductal papillary mucinous neoplasia as a large-scale clinical challenge in pancreatology. The next two parts focus on diagnosis, biomarkers and stratification that emphasize how various approaches to biomarker development are important as both prognostic and predictive tools. The final part consists of personalized treatment approaches that include preclinical models of pancreatic cancer ...
Cellular Peptidases in Immune Functions and Diseases 2
Of the many special roles played by proteolytic enzymes in immune reactions, this book addresses different aspects of membrane peptidases, signal transduction via ligation of membrane peptidases (especially of dipeptidyl peptidase IV/CD26 and aminopeptidase N/CD13), and regulation of membrane peptidases in vivo and in vitro. A number of newly discovered peptidases (including cathepsin F, W and X, carboxypeptidase X, attractin) are described, with special emphasis given to the role of peptidases in immune and defense reactions and in the pathogenesis of inflammatory and other diseases, including rheumatoid arthritis, pancreatitis, multiple sclerosis, Alzheimer's disease and tumours of various origins. The focus on the involvement of a selection of proteolytic enzymes in immune reactions and diseases is a unique feature of this multifaceted work , which combines biochemical, immunological and clinical research reports with literary reviews of the field.
Chronic Pancreatitis
This book is a concise guide to the clinical diagnosis and management of chronic pancreatitis, presenting the latest research into the disease. It focuses on pathogenesis, epidemiology, genetics, diagnosis, endoscopic and surgical treatment, and prognosis. It also offers comprehensive descriptions of 4 diagnostic methods and discusses the contemporary management of chronic pancreatitis, including conservative, ESWL, interventional and surgical treatments. The final chapter includes 6 typical case presentations, which taken together provide a standard description of this condition.
Pancreatitis and Its Complications
Diseases of the pancreas have been extremely difficult to study. Until relatively recently, the pancreas was viewed by surgeons as an organ to be avoided, given its deep retroperitoneal location and the sometimes severe consequences of manipulation. Similar difficulties have plagued careful study of the pancreas. In humans, only inf- quently have we had the opportunity to evaluate the evolution of d- eases of the pancreas; instead, we are confronted with end-stage chronic pancreatitis or acute pancreatitis with extensive necrosis of the gland. Within the past decade, revolutionary techniques in molecular biology, genetics, and animal models have begun to give us dramatic new insights into pa...
Diagnosis and Management of Acute, Chronic, and Autoimmune Pancreatitis
Pancreatitis is a condition characterized by pancreas inflammation and can be categorized into acute, chronic, and autoimmune. Common causes of acute pancreatitis include alcohol abuse, gallstones, and hyperlipidemia. Acute pancreatitis can be classified into mild, moderate, and severe forms. Mild and moderate cases typically require conservative management, while severe cases may necessitate admission to the intensive care unit and intervention. Chronic pancreatitis can be caused by alcohol abuse, idiopathic factors (unknown cause), and sometimes genetic factors. Autoimmune pancreatitis is an inflammation of the pancreas from an autoimmune etiology. Diagnosing severe acute pancreatitis is c...
Autoimmune Pancreatitis
This book provides up-to-date information on all aspects of autoimmune pancreatitis, a unique form of pancreatitis characterized clinically by frequent presentation with obstructive jaundice and dramatic response to steroids, histologically by a lymphoplasmacytic infiltrate with fibrosis, and radiologically by pancreatic enlargement. Current concepts regarding the disease and its classification into subtypes 1 and 2 are explained, and clinical, serological, and histopathological findings are carefully described. Imaging features on all the relevant modalities are illustrated, covering both the pancreas and other involved organs. Current and emerging therapeutic strategies, including steroids, immunomodulatory drugs, and rituximab, are then discussed. The reader will find the book to be an excellent aid to the diagnosis of autoimmune pancreatitis and its differentiation from pancreatobiliary malignancies, as well as a clear guide to treatment.
Clinical Pancreatology for Practising Gastroenterologists and Surgeons
Clinical Pancreatology Since the book Clinical Pancreatology for Practising Gastroenterologists and Surgeons was first published sixteen years ago, the knowledge and clinical management of pancreatic diseases have developed markedly. Thanks to the development of the translational research and the from bench to bedside concept, much progress from the lab has been applied to clinical practice. In addition, several highly relevant clinical trials published over the last years have resulted in the update and optimisation of clinical guidelines. A new and validated classification of severity and complications of acute pancreatitis is firmly rooted in clinical practice and has been the basis for t...
Clinical Pancreatology
Most patients suffering from pancreatic diseases are managed bygeneral internists, gastroenterologists and/or surgeons innon-specialized centers. Basic and clinical research inpancreatology is continuously leading to changes in the managementof pancreatic diseases, but these advances are applied to theclinical practice almost exclusively in specialized centers byspecialized groups. The books and journals currently available are directed atpancreatologists and the information does not reach most generalclinicians and surgeons who treat patients suffering frompancreatic diseases. The aim of this book is to provide practisinggastroenterologists and surgeons with clear information regardingthe diagnosis and treatment of pancreatic diseases.
Autoimmune (IgG4-related) Pancreatitis and Cholangitis
Autoimmune (IgG4-related) Pancreatitis and Cholangitis reviews the breadth of clinical, imaging, histological, laboratory, and imaging features associated with IgG4-associated systemic disease, especially AIP and IAC. Written by experts in their fields, each chapter includes an overview of existing data as well as the most up-to-date scientific information and emerging data. The book also addresses areas of uncertainty and controversy, briefly highlighting clinical and research needs relative to the respective topic. Comprehensive and easy to use, Autoimmune (IgG4-related) Pancreatitis and Cholangitis is a valuable resource for physicians who deal with or are interested in these complex disease processes, including gastroenterologists, hepatologists, and surgeons.
