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Sponges (phylum Porifera) are known to be very rich sources for bioactive compounds, mainly secondary metabolites. Main efforts are devoted to cell- and mariculture of sponges to assure a sustainable exploitation of bioactive compounds from biological starting material. These activities are flanked by improved technologies to cultivate bacteria and fungi which are associated with the sponges. It is the hope that by elucidating the strategies of interaction between microorganisms and their host (sponge), by modern cell and molecular biological methods, a more comprehensive cultivation of the symbiotic organisms will be possible. The next step in the transfer of knowledge to biotechnological applications is the isolation, characterization and structural determination of the bioactive compounds by sophisticated chemical approaches.
In September 2021 a very special academic conference took place: T2051MCC - The 2051 Munich Climate Conference. Researchers from across the academic spectrum assembled to discuss climate change. What made it special was that everyone held their lecture as if it took place in an imagined year 2051. The theatre collective Büro Grandezza had released an open call for contributions to a conference in Munich. Almost 50 researchers wrote papers on climate narratives, geoengineering, coastal adaptation and other topics. This particular framework allowed them to break out of the constraints of the current discourse without neglecting methodology or thematic sharpness.
Entanglement and (de-)coherence arguably define the central issues of concern in present day quantum information theory. Entanglement being a consequence of the quantum mechanical superposition principle for composite systems, a better understanding of the environment-induced destruction of coherent superposition states is required to devise novel strategies for harvesting quantum interference phenomena. The present book collects a series of advanced lectures on the theoretical foundations of this active research field, from mathematical aspects underlying quantum topology to mesoscopic transport theory. All lectures start out from an elementary level and proceed along a steep learning curve. This makes the material particularly suitable for student seminars on the more fundamental theoretical aspects of quantum information, and equally useful as supplementary reading for advanced lectures on this topic.
This textbook is a practical guide to the use of small animal imaging in preclinical research that will assist in the choice of imaging modality and contrast agent and in study design, experimental setup, and data evaluation. All established imaging modalities are discussed in detail, with the assistance of numerous informative illustrations. While the focus of the new edition remains on practical basics, it has been updated to encompass a variety of emerging imaging modalities, methods, and applications. Additional useful hints are also supplied on the installation of a small animal unit, study planning, animal handling, and cost-effective performance of small animal imaging. Cross-calibration methods and data postprocessing are considered in depth. This new edition of Small Animal Imaging will be an invaluable aid for researchers, students, and technicians involved in research into and applications of small animal imaging.
Advanced .NET Remoting is the first book that really offers in-depth coverage of the .NET Remoting Framework. The first part of the book covers everything a developer needs to know to use to the Framework and its capabilities in real world applications (Server Activated Objects vs. Client Activated Objects, formatters, channels, lifetime issues, security, configuration files, etc.) and the second part shows how the Framework really uses message sinks and sink providers, and gives in-depth advise on why and how to implement message and channel sinks.
Metallofoldamers are oligomers that fold into three-dimensional structures in a controlled manner upon coordination with metal ions. Molecules in this class have shown an impressive ability to form single-handed helical structures and other three-dimensional architectures. Several metallofoldamers have been applied as sensors due to their selective folding when binding to a specific metal ion, while others show promise for applications as responsive materials on the basis of their ability to fold and unfold upon changes in the oxidation state of the coordinated metal ion, and as novel catalysts. Metallofoldamers: From Helicates to Biomimetic Architectures describes the variety of interactions between oligomers and metal species, with a focus on non-natural synthetic molecules. Topics covered include: the major classes of foldamers and their folding driving force metalloproteins and metalloenzymes helicates: self-assembly, structure and applications abiotic metallo-DNA metallo-PNA and iDNA metallopeptides interactions of biomimetic oligomers with metal ions applications of metallofoldamers