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BMJ
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Fatty Acids and Cardiometabolic Health
The impact of fat intake on hypercholesterolemia and related atherosclerotic cardiovascular diseases has been studied for decades. However, the current evidence base suggests that fatty acids also influences cardiometabolic diseases through other mechanisms including effects on glucose metabolism, body fat distribution, blood pressure, inflammation, and heart rate. Furthermore, studies evaluating single fatty acids have challenged the simplistic view of shared health effects within fatty acid groups categorized by degree of saturation. In addition, investigations of endogenous fatty acid metabolism, including genetic studies of fatty acid metabolizing enzymes, and the identification of novel metabolically derived fatty acids have further increased the complexity of fatty acids’ health impacts. This Special Issue aims to include original research and up-to-date reviews on genetic and dietary modulation of fatty acids, and the role and function of dietary and metabolically derived fatty acids in cardiometabolic health.
Vitamin E in Human Health
Vitamin E is a well described and established fat-soluble essential micronutrient and as such has to be provided to the human body on a regular basis in order to avoid deficiency and maintain a healthy status. This is well established and also reviewed in a number of publications. However, a huge body of evidence has accumulated over the last decade, or so, which provides new insights on the mode of action of vitamin E, and the biological role of the tocopherol isomers, and sheds new light on the role of vitamin E in human health. Both fundamental knowledge gain and new data on the role and challenges of vitamin E as an essential micronutrient, including emerging evidence on clinical benefit...
Clinical Studies, Big Data, and Artificial Intelligence in Nephrology and Transplantation
In recent years, artificial intelligence has increasingly been playing an essential role in diverse areas in medicine, assisting clinicians in patient management. In nephrology and transplantation, artificial intelligence can be utilized to enhance clinical care, such as through hemodialysis prescriptions and the follow-up of kidney transplant patients. Furthermore, there are rapidly expanding applications and validations of comprehensive, computerized medical records and related databases, including national registries, health insurance, and drug prescriptions. For this Special Issue, we made a call to action to stimulate researchers and clinicians to submit their invaluable works and present, here, a collection of articles covering original clinical research (single- or multi-center), database studies from registries, meta-analyses, and artificial intelligence research in nephrology including acute kidney injury, electrolytes and acid–base, chronic kidney disease, glomerular disease, dialysis, and transplantation that will provide additional knowledge and skills in the field of nephrology and transplantation toward improving patient outcomes.
Mathematical Reviews
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Austenitic TRIP/TWIP Steels and Steel-Zirconia Composites
This open access book presents a collection of the most up-to-date research results in the field of steel development with a focus on pioneering alloy concepts that result in previously unattainable materials properties. Specifically, it gives a detailed overview of the marriage of high-performance steels of the highest strength and form-ability with damage-tolerant zirconia ceramics by innovative manufacturing technologies, thereby yielding a new class of high-performance composite materials. This book describes how new high-alloy stainless TRIP/TWIP steels (TRIP: TRansformation-Induced Plasticity, TWIP: TWinning-induced Plasticity) are combined with zirconium dioxide ceramics in powder met...
Neuro-Ophthalmology
This book presents fifty clinical cases in neuro-ophthalmology, some of which are common and some of which are rare. Each case is presented as a diagnostic and management challenge as found in clinical practice. High quality clinical photographs and images bring the cases to life alongside the diagnostic process and management decisions of an experienced specialist. A short summary of important aspects of the pathogenesis and treatment of each disease finishes each case. Neuro-Ophthalmology: Illustrated Case Studies entertains and instructs the reader and is ideal reading for doctors in training in this area, as well as general consultant neurologists and ophthalmologists.
