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Glutamate and Addiction
In Glutamate and Addiction, world-renowned scientific experts critically review all of the evidence for the role of glutamatergic systems in opiate, stimulant, and alcohol addiction. Using a variety of pharmacological, biochemical, genetic, and brain imaging techniques, these investigators show precisely how glutamate affects such addictions and how modifying certain elements of the glutamatergic system appear to alleviate particular components of addiction. Their survey takes in both clinical approaches using medications that influence glutamate and cutting-edge preclinical approaches that manipulate specific subtypes of glutamate receptors or specific substrates of the "glutamate cascade" to determine their roles in various addictive states.
Fetal and Neonatal Brain Injury
This book evaluates the numerous events in pregnancy, labor, and post-partum care that can lead to brain damage in newborn infants. The mechanisms by which the brain is damaged, as well as the approaches to treatment and most importantly, prevention of injury are detailed. Sixteen new chapters have been added to the Second Edition, and all the others have been fully updated. New chapters cover subjects such as ischemic cell injury, reperfusion injury, experimental models of perinatal brain injury, hypoxemic-ischemic encephalopathy, congenital malformations of the brain, perinatal infections, and metabolic disorders in the developing CNS. A chapter devoted exclusively to hemorrhagic lesions of the brain has been added as well. The new edition incorporates the most recent advances in neurology, neurosurgery, and neuroimaging, including the rapidly improving imaging techniques for identifying the extent of brain injury, the better ante- and post-partum management of infants, and the development of better understanding of the cellular mechanism of injuries to the brain.
Ludwig Klages and the Philosophy of Life
This book provides a unique overview of and introduction to the work of the German psychologist and philosopher Ludwig Klages (1872-1956), an astonishing figure in the history of German ideas. Central to intellectual life in turn-of-the-century Munich, he went on to establish a reputation for himself as an original and provocative thinker. Nowadays he is often overlooked, partly because of the absence of an accessible and authoritative introduction to his thought; this volume offers just such a point of entry. With an emphasis on applicability and utility, Paul Bishop reinvigorates the discourse surrounding Klages, providing a neutral and compact account of his intellectual development and h...
Monographic Series
None
Manual of Stroke Models in Rats
During the last few years, exciting new insights into mechanisms and treatment of stroke have been obtained from animal experiments. Hence, the use of animal models to induce stroke are of paramount importance as research tools. While a few articles on this topic have been published in select journals, until now there has not been a systematic tech
Contemporary German Fiction Writers
Contains alphabetically arranged essays that provide biographical and critical information about significant contemporary German fiction writers; each with a list of principal works and a bibliography.
Neuroprotection
his latest Society of Cardiovascular Anesthesiologists monograph brings readers up-to-date on protecting patients from neurological problems while undergoing cardiovascular surgery
