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This book is the first in a new series entitled ''Advances in Circadian Physiology." Our aim in this and subsequent volumes is to document and critically analyze the state of knowledge on biological clocks, circadian rhythms and their applications to human health, safety, performance and productivity. In the past twenty years, scientists have uncovered an elegant system of biological clocks in the brain that govern the daily rhythms of sleep and alertness, hormone levels and temperature and a myriad other aspects of body function. From the first identification of the suprachiasmatic biological clock in the early 1970s, this field of research has exploded in information and implication. These biological clocks, so perfectly attuned to the pace of a bygone era, are the root cause of the human fatigue, error, accidents and reduced productivity precipi tated by the around-the-clock challenges of today's industry and society. Research on these clocks offers the promise of fundamental solutions which can help the human race adjust physiologically to the technology-paced world we have created.
Developing the second edition of Neural Development and Stem Cells was neces- tated by the rapid increase in our knowledge of the development of the nervous system. It has become increasingly clear that stem cells are a heterogeneous population that changes extensively during development. Perhaps the most important advance in our understanding of stem cell behavior has been the realization that regionalization of stem cells occurs early in development and this bias toward differentiation in phe- types of neurons or cells characteristic of a particular part of the brain appears to persist even after prolonged culture. We have therefore included additional chapters on olf- tory epithelial stem...
Much of contemporary behavioral or cognitive neuroscience is concerned with discovering the neural basis of psychological processes such as attention, cognition, consciousness, perception, and memory. In sharp divergence from this field, An Odyssey Through the Brain, Behavior and the Mind can be regarded as an elaborate demonstration that the large scale features of brain electrical activity are related to sensory and motor processes in various ways but are not organised in accordance with conventional psychological concepts. It is argued that much of the traditional lore concerning the mind is based on prescientific philosophical assumptions and has little relevance to brain function. The first ten chapters of An Odyssey Through the Brain, Behavior and the Mind give a personal account of how the various discoveries that gave rise to these views came to be made. This is followed by discussions of brain organization in relation to behavior, learning and memory, sleep and consciousness, and the general problem of the mind.
Recent concerns over the possible hazards of electrical and magnetic fields in the home and workplace are comprehensively addressed within this book. The chapters contain detailed research on the biological effects of electric and magnetic fields, and evidence for and against any interaction of electromagnetic fields (EMFs) and the biological systems. - The relative risk of exposure to EMFs - Putative behavioral and neural effects of EMFs - EMF effects on cells
This book presents a series of essays on neuroscientific aspects of human nature and instinctive behavior, individually acquired (learned) behavior, human bipedal locomotion, voluntary movement, and the general problem of how the brain controls behavior. The author argues that concepts of the mind based on ancient Greek philosophy are past usefulness, and that modern animal behavior studies provide a better guide to the functional organization of the brain.
In this thoroughly updated and revised edition of his much praised book, Paul L. Wood and a panel of leading researchers capture these new developments in a masterful synthesis of what is known today about the inflammatory mediators and cells involved in neurodegenerative diseases. This second edition contains extensive updates on the mediators produced by microglia and their role in neuroinflammatory-induced neuronal lysis. There is also increased coverage of the animal models used in the study of neuroinflammatory mechanisms, of the new imaging methods that allow the noninvasive evaluation of microglial activation in human neurodegernerative disorders, and of the role of neuroinflammation in amyloid-dependent neuronal lysis.
A distinguished international panel of authors define our current understanding of neuronal damage after ischemia and critically review the significant recent developments and progress in cerebrovascular accident (CVA) drug trials, both in animal models and in the clinical setting. These leading basic and fundamental authorities survey such important new drugs as calcium-influx inhibitors, free-radical scavenging drugs, glutamate and glycinergic antagonists, and immune suppressors. They also evaluate all the latest findings concerning calcium homeostasis, glutamate toxicity, gene activation, and the role of free radicals, glycine, and hormones. Chapters devoted to the neuroimaging of stroke, clinical trials, and the role of cerebral immune activation complete this informative collection of cutting-edge reviews.
A novel account of pollution in the Hebrew Bible, from its embodied origins, to its metaphorical expression in moral discourse.