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Mechanosensing Biology
Mechanical stress is vital to the functioning of the body, especially for tissues such as bone, muscle, heart, and vessels. It is well known that astronauts and bedridden patients suffer muscle and bone loss from lack of use. Even the heart, in pumping blood, causes mechanical stress to itself and to vascular tissue. With the loss of mechanical stress, homeostasis becomes impaired and leads to pathological conditions such as osteopenia, muscle atrophy, and vascular tissue dysfunction. In elderly populations, such mechanical pathophysiology, as well as the mechanical activities of locomotor and cardiovascular systems, is important because skeletal and heart functions decline and cause diseases in other organs. In this monograph, mechanical stress is discussed by experts in the field with respect to molecular, cellular, and tissue aspects in relation to medicine. Covering topics such as gravity and tissues and disuse osteoporosis, the book provides the most up-to-date information on cutting-edge advancements in the field of mechanobiology and is a timely contribution to research into locomotor and circulatory diseases that are major problems in contemporary society.
Principles of Bone Biology
Principles of Bone Biology provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. It is the essential resource for anyone involved in the study of bone biology. Bone research in recent years has generated enormous attention, mainly because of the broad public health implications of osteoporosis and related bone disorders. - Provides a "one-stop" shop. There is no need to search through many research journals or books to glean the information one wants...it is all in one source written by the experts in the field - The essential resource for anyone involved in the study of bones and bone diseases - Takes the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics - Readers can easily search and locate information quickly as it will be online with this new edition
Clinical Impact of Bone and Connective Tissue Markers
For many years, biochemical tests have been widely used for the diagnosis, classification, and monitoring of bone and connective tissue disease. However, shortcomings in terms of the specificity and sensitivity of such tests have prompted continual questioning about their clinical usefulness.This book, based on a meeting organized jointly by the University of Uppsala and Pharmacia Diagnostics AB, reviews our current understanding of basic bone and connective tissue biochemistry and the clinical role of biochemical markers specific to related diseases, with special reference to rheumatoid arthritis and osteoporosis.
New Actions of Parathyroid Hormone
Shaul G. Massry Division of Nephrology, The University of Southern California, School of Medicine Los Angeles, California In the last two decades evidence has accumulated indicating that parathyroid hormone may exert a multitude of effects on many cells and a variety of organs beyond its classical targets: the kidney and the bone. These efforts have been spearheaded by nephrologists. The interest of this group of clinicians-scientists stems from the fact that patients with renal failure have secondary hyperparathyroidism and markedly elevated blood levels of PTH (1,2). If this hormone does act on various organs, it becomes plausible that excess blood levels of PTH may be harmful in these pat...
The Chemistry and Biology of Mineralized Tissues
The proceedings of the Third International Conference (on title) held in Chatham, Mass., October, 1988. Presents coverage of many areas of the skeletal system, including new experimental techniques, research areas, ideas, and hypotheses. Discusses at length the chemical nature and structure of organic matrix components and their influence with respect to regulation of cell function. Annotation copyrighted by Book News, Inc., Portland, OR
Cell and Molecular Biology of Vertebrate Hard Tissues
Brings together the latest research in the cellular and molecular biology of bones and teeth, including applications to medical and dental practice. An interdisciplinary group of contributors addresses control of bone formation, resorption and remodelling, osteoblast differentiation and osteoclast activity, factors influencing dental extracellular matrix biomineralization, non-collagen proteins in bone and their function, hormonal regulation of bone growth, and more.
Cellular and Molecular Biology of Bone
Written by well-known experts in their respective fields, this book synthesizes recent work on the biology of bone cells at the molecular level. Cellular and Molecular Biology of Bone covers the differentiation of these cells, the regulation of their growth and metabolism, and their death resorption. The authors' special comprehensive treatment of the cellular and molecular mechanisms of bone metabolism makes this book a unique and valuable tool. Cellular and Molecular Biology of Bone provides interested readers-with concise state-of-the-art reviews in bone biology that will enlarge their scope and increase their appreciation of the field. Research in this area has intensified recently due to the increasing incidence of osteoporosis. The editor hopes an understanding of the basic biology of this disease will prove relevant to its prevention and treatment.
Shakespeare in Asia
Contributors from a wide variety of backgrounds debate how and why Shakespeare has been used and reinvented in contemporary Asia.
