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Cardiac Drug Safety
Ensuring the safety of new medical products remains a major challenge for the pharmaceutical industry. Cardiac safety, particularly drug-induced heart rhythm abnormalities, remains an important cause of pipeline attrition and has resulted in countless major product recalls or label changes. The risk of encountering this major adverse event continues to shape the drug development and regulatory landscape. Extensive research over the past decade has shed light on the root causes of arrhythmias that are triggered by medications and has helped drive, and optimize, drug safety testing. However, current cardiac safety platforms have several limitations and there remains a pressing unmet need to im...
Congressional Record
The Congressional Record is the official record of the proceedings and debates of the United States Congress. It is published daily when Congress is in session. The Congressional Record began publication in 1873. Debates for sessions prior to 1873 are recorded in The Debates and Proceedings in the Congress of the United States (1789-1824), the Register of Debates in Congress (1824-1837), and the Congressional Globe (1833-1873)
That High Design Of Purest Gold: A Critical History Of The Pharmaceutical Industry, 1880-2020
This book is a history of medicines and the commercial actors that make and sell them, covering the 140 years since the modern pharmaceutical industry came into being. It is written in a lively and accessible way, aiming at a general audience that combines historical narrative with fascinating case studies on drug discovery and commercialization, from the rat poison that became warfarin, to a cardiovascular treatment that was turned into Viagra. In a non-partisan way it also examines some of the less noble manifestations of corporate behavior, concluding with an agenda for reform.It is hard to think of anything nobler than to bring to the world a medicine that saves lives. And over 140 years...
Orphan Monster Spy
"Like Inglourious Basterds for tweens, this clever YA title features Sarah, a blond, blue-eyed Jewish girl in 1939 Germany."--The New York Post After her mother is shot at a checkpoint, fifteen-year-old Sarah finds herself on the run from the Nazis in Third Reich-ruled Germany. While trying to escape, Sarah meets a mysterious man with an ambiguous accent, a suspiciously bare apartment, and a lockbox full of weapons. He's part of the secret resistance against the Reich, and he needs her help. Sarah is to hide in plain sight at a boarding school for the daughters of top Nazi brass, posing as one of them. She must befriend the daughter of a key scientist to gain access to the blueprints for a bomb that could destroy the cities of Western Europe, and steal them. Sarah may look like the rest of the girls, innocent, blonde-haired, and young, but she refuses to become one of the monsters she's surrounded by. She's a brilliant con artist, convincing them she's one of them even as she lives in terror of being found out. And she's determined to get her revenge on them all.
