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Manual of Pediatric Therapeutics
Thoroughly updated for its Seventh Edition, this practical quick-reference manual presents authoritative patient management guidelines based on the extensive clinical experience at The Children's Hospital in Boston. Coverage includes normal newborn, well-child, and adolescent care, acute care, disorders of each organ system, behavioral disorders, and management of the child with developmental disabilities and specialized health care needs. The text includes numerous easy-to-scan tables and a popular "A to Z" drug formulary.
Disorders of Hemoglobin
This book is a completely revised new edition of the definitive reference on disorders of hemoglobin. Authored by world-renowned experts, the book focuses on basic science aspects and clinical features of hemoglobinopathies, covering diagnosis, treatment, and future applications of current research. While the second edition continues to address the important molecular, cellular, and genetic components, coverage of clinical issues has been significantly expanded, and there is more practical emphasis on diagnosis and management throughout. The book opens with a review of the scientific underpinnings. Pathophysiology of common hemoglobin disorders is discussed next in an entirely new section devoted to vascular biology, the erythrocyte membrane, nitric oxide biology, and hemolysis. Four sections deal with α and β thalassemia, sickle cell disease, and related conditions, followed by special topics. The second edition concludes with current and developing approaches to treatment, incorporating new agents for iron chelation, methods to induce fetal hemoglobin production, novel treatment approaches, stem cell transplantation, and progress in gene therapy.
Iron Disorders, an Issue of Hematology/Oncology Clinics
This issue of Hematology/Oncology Clinics, guest edited by Drs. Matthew Heeney and Alan Cohen, is devoted to Iron Disorders. Articles in this issue include: Hereditary Hemochromatosis (HFE and Non-HFE); Iron Refractory Iron Deficiency Anemia (IRIDA); Sideroblastic Anemia; Anemia of Chronic Disease/Inflammation; Pathophysiology of Transfusional Iron Overload; Transfusional Iron Overload and Iron Chelation Therapy; Iron Overload and its Management in Non-Transfusion-Dependent Thalassemia; Treatment of Iron Deficiency Anemia; and Iron Overload Assessment.
Colorectal Cancer, An Issue of Hematology/Oncology Clinics
This issue of Hematology/Oncology Clinics of North America, devoted to Colorectal Cancer, is edited by Dr. Leonard B. Saltz. Articles in this issue include: Diet and Lifestyle Influences on Colorectal Cancer; Diagnosis and Management of Germline and Somatic Mutations in Mismatch Repair-deficient Colorectal Cancer; Adjuvant Chemotherapy in Stage II, III, and Resected Stage IV Colon Cancer; Predictive and Prognostic Markers in the Treatment of Colorectal Cancer; Surgical Management of Hepatic Metastases of Colorectal Cancer; Combination Therapies in Colorectal Cancer Treatment; A Critical Look at Management of Peritoneal Metastases of Colorectal Cancer; Non-surgical Management of Rectal Cancer; and Ablative Therapies for Metastatic Colorectal Cancer.
Multiple Myeloma, An Issue of Hematology/Oncology Clinics
This issue of Hematology/Oncology Clinics of North America, devoted to Multiple Myeloma, is edited by Dr. Kenneth C. Anderson. Articles in this issue include: Monoclonal Gammopathy of Undetermined Significance and Smoldering Multiple Myeloma; Diagnosis and Risk Stratification in Myeloma; Treatment of Newly Diagnosed Transplant Eligible Patients; Treatment of Newly Diagnosed Transplant Ineligible Patients; Treatment of Relapsed/Refractory Myeloma; Maintenance Therapy; Novel Targeted Therapies; Novel Immune-based Therapies; Allotransplantation in Myeloma; and Waldenstrom’s Macroglobulinemia.
Paroxysmal Nocturnal Hemoglobinuria and Related Disorders
Few publications focus on the mysterious, genetically acquired disease paroxysmal nocturnal hemoglobinuria (PNH) and the related "intractable" disorders—aplastic anemia and myelodysplastic syndromes. Now, however, the latest understanding of the clinical and molecular genetic aspects of PNH is summarized here in the proceedings of the International Symposium held in Tokyo in 2001. Major topics reviewed include the molecular mechanisms of the PIG-A gene mutation; complement activation and inhibitors; experimental animal models; pathogenesis; the history of PNH research; the natural history of the disease; the mechanism of PNH clone expansion; the emergence of PNH clones under bone marrow failure syndromes; and treatment of the disease by immunosuppressive agents and stem cell transplantation. This book provides an invaluable summary of current research on the fundamental aspects of PNH pathology, presented by renowned experts in the field.
Pathophysiology of Blood Disorders
A concise full-color review of the mechanisms of blood diseases and disorders – based on a Harvard Medical School hematology course 4 STAR DOODY'S REVIEW! "This is a superb book. Deceptively small, yet packs a wallop. The emphasis on principles instead of practice is welcome....The text is clear, concise, and surprisingly approachable for what could have been a very dense and dry discussion. I could not put this book down and read it entirely in one sitting. When was the last time anyone found a hematology textbook so riveting?"--Doody's Review Service Hematological Pathophysiology is a well-illustrated, easy-to-absorb introduction to the physiological principles underlying the regulation ...
Comprehensive Pediatric Hospital Medicine E-Book
Introducing the newest comprehensive reference designed specifically for the growing specialty of hospital-based pediatrics. This comprehensive new reference not only brings you the most up-to-date, evidence-based approaches to hospital-based pediatric care, but also covers issues related to staffing a unit; financial, legal and ethical topics, and how a hospitalist program communicates and relates to its referring providers and consulting staff. You'll find it a vital addition to the shelf of anyone who cares for pediatric patients in the hospital. Implement today's best evidence and literature based approaches for a full range of clinical challenges. Easily locate information relevant to your particular areas of interest with comprehensively organized, highly formatted coverage. Make clinical decisions efficiently thanks to numerous diagnostic and therapeutic algorithms. See dermatologic conditions and physical signs and symptoms. Benefit from the experience of editors from two powerhouse institutions - Children's Hospital of Philadelphia and Children's Hospital of Boston.
Benign Hematologic Disorders in Children, An Issue of Pediatric Clinics of North America
This issue will provide a current update on diagnosis, treatment, and management of children with being hematological disorders. Dr. Callaghan has put together a comprehensive issue with clinical reviews written by top experts in the field. Articles are devoted to the following topics: Hemophilia; Sickle cell acute chest; Sickle cell drugs; Sickle cell gene therapy; Sickle cell menses and pain; Pediatric DVT; Atypical HUS; von Willebrand Disease; Female bleeding; Functional platelet disorders; Hemolytic anemia; Advocacy in hematology; ITP; and Acquired aplastic anemia. Readers will come away with the current clinical information they need to improve clinical outcomes.
Nathan and Oski's Hematology and Oncology of Infancy and Childhood E-Book
Written by the leading names in pediatric oncology and hematology, Nathan and Oski's Hematology and Oncology of Infancy and Childhood offers you the essential tools you need to overcome the unique challenges and complexities of childhood cancers and hematologic disorders. Meticulously updated, this exciting full-color set brings together the pathophysiology of disease with detailed clinical guidance to provide you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children. - Form a definitive diagnosis and create the best treatment plans possible with comprehensive coverage of all pediatric cancers, including less-common tumors, as well as all hem...
