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Imaging Biomarkers in Epilepsy
Assembles world-class expertise on clinical and molecular imaging-derived biomarkers, presenting neuroimaging in epilepsy in a broad neuroscientific context.
Neurology
Neurology: A Queen Square Textbook, second edition, is a fully revised and updated companion that demonstrates the rapid pace of advancement within clinical neurology and applied neuroscience A comprehensive and practical overview of current developments within clinical neurology, synthesising clinical neurology with translational research Expertly edited and written by neurologists, neuroscientists and neurosurgeons working at Queen Square, advised by an distinguished International Editor team to present a global perspective Introductory chapters summarise the basic sciences underpinning the practice of clinical neurology, including genetics, channelopathies, immunology, neurophysiology and...
Neuropsychology in the Care of People with Epilepsy
Having appeared in the 1930s in Montreal, standardised neuropsychological evaluation has become an essential tool in the clinical diagnosis and evaluation of surgical epileptic patients. Nevertheless, despite great progress over the last 20 to 30 years in the diagnosis and medical treatment of epilepsy, clinical neuropsychology still remains largely associated with surgical epilepsy, particularly surgery of the temporal lobe. Clinical neurology has still not managed to clear a way in the daily practice with patients with all types of epilepsy despite significant advances in cognitive neuroscience and a large number of clinical studies on epilepsy and cognition. How is it that there are only rarely major advances in the field of clinical neuropsychology? It has long been time for this question to be asked, and for an attempt to be made to bring about changes. This was the aim of the Toronto workshop and the result of this book. Every approach was debated, providing important elements to reflect on and allowing a great forum for exchanges. This book includes the communications from the main participants and comments from some others on specific subjects.
Inflammation and Epilepsy: New Vistas
This book provides comprehensive information, both for clinicians and scientists, on the basic mechanisms, clinical features, and therapeutic approaches to epilepsy as an inflammatory disease. Inflammation has been for many years considered as an etiologic player (and a therapeutic target) for a specific group of epilepsies. However, it turns out that this concept underestimated the impact of inflammation in seizure disorders. Many accepted therapies for non-inflammatory epilepsies act in part as an inflammatory drug. The CNS actively responds to acute immune challenges by altering body temperature, stimulating the HPA axis, as well as up- and down-regulating specific sympathetic pathways.
Festschrift – The Institute of Nuclear Medicine
The Institute of Nuclear Medicine, founded in 1961, celebrates with this Festschrift, its Golden Jubilee. It has been a remarkable 50 years of progress of the radionuclide tracer methodology. From initial, physiology based experimentation, a full independent medical discipline evolved, and with it, a comprehensive clinical service. Diagnosis and Treatment with radiotracers have established the basis for Nuclear Medicine. Technological advances have permeated the field like none other, its multidisciplinary character and its translational research are embedded in the history of the Institute and its success. Recent and latest advances in the field promise a future as bright as has been witnessed and documented in the last 50 years.
Quantification of Brain Function Using PET
Functional imaging of the brain is one of the most rapidly advancing areas of neuroscience and Positron Emission Tomography (PET) plays a major role in this progress. This book provides a comprehensive overview of the current status of PET and state-of-the-art neuroimaging. It is comprised of summaries of the presentations by experts in the field. Topics covered include radiotracer selection, advances in instrumentation, image reconstruction and data analysis, and statistical mapping of brain activity. This book focuses on the accuracy of the functional image and the strategies for addressing clinical, scientific, and diagnostic questions.Covers the PET imaging process from tracer selection to analysis and interpretationContains 79 concise reports with abundant illustrationsThe definitive state-of-the-art book for functional neuroscience with PET
The Causes of Epilepsy
Causation is an aspect of epilepsy neglected in the scientific literature and in the conceptualization of epilepsy at a clinical and experimental level. It was to remedy this deficiency that this book was conceived. The book opens with a draft etiological classification that goes some way to filling the nosological void. The book is divided into four etiological categories: idiopathic, symptomatic, cryptogenic, and provoked epilepsies. Each chapter considers topics in a consistent fashion, dealing with the phenomenon of epilepsy in each etiology, including its epidemiology, clinical features and prognosis, and any specific aspects of treatment. The book is a comprehensive reference work, a catalogue of all important causes of epilepsy, and a clinical tool for all clinicians dealing with patients who have epilepsy. It is aimed at epileptologists and neurologists and provides a distillation of knowledge in a form that is helpful in the clinical setting.
PET and SPECT in Neurology
This book provides a comprehensive overview of the use of PET and SPECT in not only classic neurodegenerative disorders but also cerebrovascular disorders, brain tumors, epilepsy, head trauma, coma, sleeping disorders, and inflammatory and infectious diseases of the CNS. The new edition has been revised and updated to reflect recent advances and includes additional chapters, for example on the use of artificial intelligence and machine learning in imaging data analysis, the study of brain connectivity using PET and SPECT images, and the role of PET imaging in modulation of brain functioning by deep brain stimulation. The authors are renowned experts whose dedication to the investigation of n...
Why Does Coffee Make You Poop?
Uncover the answers to the world’s most intriguing, entertaining, and funny questions with this best-ever trivia book from best-selling author Andrew Thompson. Shock and astound at your next dinner party with this “Best Of” trivia collection from the author of Can Holding in a Fart Kill You? This collection was created for all the curious adults who desire to have the answer to some of life’s strangest questions, including: Why can’t you tickle yourself? Why does coffee make you poop? Which came first, the chicken or the egg? Does bigfoot exist? Does an apple a day keep the doctor away? If a tree falls in a forest, does it make a sound? And more crazy questions for any curious mind out there. Why Does Coffee Make You Poop? is perfect for white elephant gift exchanges, stocking stuffers, or lovers of strange, obscure, and sometimes hilarious trivia.
Reflex Epilepsies: progress in understanding
Reflex epilepsies can provide a qualitative and quantitative viewpoint of the complexities of ictogenesis. The various chapters in this book examine the factors that can trigger a seizure, such as hot water, food, contact and movement, music and emotions. The relationship between several reflex epilepsy mechanisms and juvenile myoclonic epilepsy is discussed along with the significance of their occurrence in syndromes, enhancing our understanding of current epilepsy nosology. The conventional dichotomy appears outdated, while functional studies of trigger mechanisms are moving more towards central nervous system subsets acting as pathological networks that produce seizures in generalized and focal epilepsies.
