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The paper presents the results of a survey (2009-2011) which aimed at the analysis of the awareness level of junior college students regarding climate change (CC) and its consequences. Based on interviews conducted in the emerging megacity Hyderabad, India and on an institutional analysis of the education sector, teaching modules for junior colleges were be developed to augment knowledge on climate change in future generations. The topic is linked with the research work of the megacity project "Sustainable Hyderabad" (www.sustainable-hyderabad.in) where climate change impacts are being analysed and mitigation and adaptation measures are being developed. The work presented explores communication strategies which target climate friendly and energy efficient lifestyles and consumption patterns. Furthermore it intends to integrate local knowledge and needs of affected groups in the development of communication and participation strategies to make them efficient and to activate the civil society to take self-initiative.
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This volume presents modern and enhanced methods that detail techniques to perform proteomics analyses dedicated to biomarker discovery for human health. Chapters guide readers through pre/post analytical factors, protocols for the preparation of extracellular vesicles and exosomes, and various analytical pipelines including Data Independent Acquisition (DIA), discovery, as well as targeted and top-down proteomics analysis workflows. Bioinformatics tools and workflows to select and evaluate candidate biomarkers or combinations of biomarkers are also presented. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Proteomics for Biomarker Discovery: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Abstract: RNA vaccines are efficient preventive measures to combat the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. High levels of neutralizing SARS-CoV-2 antibodies are an important component of vaccine-induced immunity. Shortly after the initial two mRNA vaccine doses, the immunoglobulin G (IgG) response mainly consists of the proinflammatory subclasses IgG1 and IgG3. Here, we report that several months after the second vaccination, SARS-CoV-2-specific antibodies were increasingly composed of noninflammatory IgG4, which were further boosted by a third mRNA vaccination and/or SARS-CoV-2 variant breakthrough infections. IgG4 antibodies among all spike-specific IgG a...
Understanding Global Politics is a pioneering work, which analyses contemporary issues such as climate change, migration, nuclear proliferation, terrorism as well as feminist perspective on International Relations. It covers the various dimensions of globalisation which affects on the accelerating world. The intergovernmental agencies such as International Atomic Energy Agency (IAEA), International Court of Justice as well as the United Nations, are instrumental in directing the energies towards the control of proliferation of nuclear weapons. The last section of the book deliberates on the global shifts, power and governance in a fast changing world order. The salience of global, regional and economic groupings like WTO, IMF, World Bank, BRICS, EU, etc are covered in great detail. The book presents an opportunity to engage in Applied Global Politics and explore the core concept by students of Political Science, International Relations, as well as refresher for scholars of defence and security studies.